Purpose: Continuous tumor position measurement coupled with a tumor tracking system would result in a highly accurate radiation therapy system. Previous internal position monitoring systems have been limited by fluoroscopic radiation dose and low delivery efficiency. We aimed to incorporate a continuous, electromagnetic, threedimensional position tracking system (Calypso 4D Localization System)...

the aim of radiation therapy treatment planning is to achieve an optimal balance between delivering a high dose to target volume and a low dose to healthy tissues. in order to refrain any complications resulting from the dose to the surrounding normal organs, the role of treatment plan has been critically evaluated in term of how large the volume or mass of normal tissues exposed in the radiati...

A 77-year-old male patient with unresected malignant pleural mesothelioma, clinical stage T3N0M0 according to the New International Staging System for Diffuse Malignant Pleural Mesothelioma, received intensity-modulated radiotherapy (IMRT) with a simultaneous integrated boost (SIB) after 6 cycles of chemotherapy with cisplatin and pemetrexed. SIB-IMRT delivered 40.5 Gy (1.5 Gy/fraction) to the ...

BACKGROUND Concurrent chemoradiotherapy (CRT) is the standard of care in patients with limited-stage small cell lung cancer (SCLC). Treatment with conventional x-ray therapy (XRT) is associated with high toxicity rates, particularly acute grade 3+ esophagitis and pneumonitis. We present outcomes for the first known series of limited-stage SCLC patients treated with proton therapy and a dosimetr...

PURPOSE The aim of this retrospective cohort study was to assess treatment outcome, and acute pulmonary and esophageal toxicity using intensity modulated (sequential/concurrent chemo)radiotherapy (IMRT) in locally advanced stage III non-small cell lung cancer (NSCLC). METHODS AND MATERIALS Eighty-six patients with advanced stage NSCLC, treated with either IMRT only (66 Gy) or combined with (s...

Malignant thymomas are rare epithelial neoplasms of the anterior superior mediastinum that are typically invasive in nature and have a higher risk of relapse that may ultimately lead to death. Here we report a case of an advanced malignant thymoma that was successfully treated with neoadjuvant chemotherapy followed by surgical resection and subsequently with advanced and novel radiation therapy...

Journal of Medical Physics ¦ Volume 42 ¦ Issue 2 ¦ April-June 2017 100 We highly appreciate your comments. It is well known that there are considerable target position uncertainties during breast radiotherapy. These uncertainties result from respiratory motions, tissue and organ deformation, daily patient setup, and other causes. Respiratory gating and breath control can reduce the target posit...

With intensity-modulated radiotherapy (IMRT), it is important that the inverse planning process yields the most appropriate dose distribution for the patient and that the delivered dose then corresponds to the planned dose. This paper presents methods by which the inverse planning and delivery of segmental (step-and-shoot) IMRT can be verified, and gives results for a typical treatment planning...

PURPOSE For patients with left-sided breast cancers, radiation treatment to the intact breast results in high doses to significant volumes of the heart, increasing the risk of cardiac morbidity, particularly in women with unfavorable cardiac anatomy. We compare helical tomotherapy (TOMO) and inverse planned intensity modulated radiation therapy (IMRT) with three-dimensional conformal radiothera...