نتایج جستجو برای: lps pcr

تعداد نتایج: 198566  

2016
Songül Tosun Sabrina Fried Bernd Niggemann Kurt S. Zänker Thomas Dittmar

TLRs are important receptors of cells of the innate immune system since they recognize various structurally conserved molecular patterns of different pathogens as well as endogenous ligands. In cancer, the role of TLRs is still controversial due to findings that both regression and progression of tumors could depend on TLR signaling. In the present study, M13SV1-EGFP-Neo human breast epithelial...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید باهنر کرمان - دانشکده علوم پایه 1390

لیپوپلی ساکارید (lps) )یک ماکرومولکول باکتریایی منحصر به فرد است که فقط در غشای لیپیدی دولایه ای که دیواره ی سلولی باکتری های گرم منفی از قبیل اشرشیاکلای را پوشانده یافت می شود. lps یک هدف مخصوص برای تشخیص به وسیله سیستم ایمنی ذاتی وشروع پاسخ ایمنی است به طور معمول برای تحریک پاسخ مرحله حاد(apr )وبیماری بی اشتهایی تحت شرایط تجربی از آن استفاده می شود. پاسخ فاز حاد یکسری واکنش های رفتاری و فیز...

2016
Zheng-de Xi Chang-yi Xie Ye-bin Xi

BACKGROUND Fibroblast proliferation is a common manifestation of chronic inflammatory diseases, including rheumatoid arthritis (RA), Crohn's disease and ulcerative colitis, etc. To alleviate patient suffering, the mechanism underlying fibroblast proliferation should be elucidated. METHODS CCK-8 assay was used to assess the stimulatory effect of LPS and macrophage migration inhibitory factor (...

Journal: :iranian journal of allergy, asthma and immunology 0
yan yang institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china hanxiao sun institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china xiuying li institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china qing ding institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china pijin wei institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china jingguang zhou institute of genomic medicine research, college of pharmacy, jinan university, guangzhou, 510632, people’s republic of china

our prior study found  that transforming growth factor  beta-induced (tgfbi) is  an important negative regulator in tlr-induced inflammation. however, whether tgfbi may affect inflammation during lipopolysaccharide (lps)-induced endotoxin tolerance (et) is still unclear.this study aimed to investigate whether tgfbi was involved in the mechanisms of et in human through dampening nuclear factor-k...

پایان نامه :وزارت علوم، تحقیقات و فناوری - پژوهشگاه ملی مهندسی ژنتیک وزیست فناوری 1392

. از بخش های ریشه، ساقه و برگ مورخوش، کالوس القا و بعد از سه دوره واکشت کالوس ها، عصاره آبی آنها و نیز عصاره آبی و اسانس برگ خشک گیاه استخراج شد. کروماتوگرافی جرمی(gc mass) انجام شده برای اسانس نشان داد که دو ترکیب کامفور و لینالول، ترکیبات اصلی موجود در اسانس گیاه هستند، لینالول و کامفور دارای اثرات ضد التهابی می باشند. سلول های مخلوط گلیال موش صحرایی در محیط کشت dmem حاوی 10% از fbs کشت داده ...

Journal: :Journal of basic microbiology 2005
F Fernández J Gutiérrez J Linares A Rojas A Sorlózano

The relationship between Chlamydophila pneumoniae (Cp) infection and peripheral arterial occlusive disease (PAD) was studied by analyzing clinical samples from 95 patients with PAD and 100 controls. The following investigations were conducted: IgG and IgA against lipopolysaccharide (LPS) and against purified Cp-specific antigens from elementary bodies (EB) with ELISA; anti-EB IgG, with MIF; Cp ...

Journal: :The Journal of pharmacology and experimental therapeutics 2013
Jürgen Knobloch Maria Feldmann Chiara Wahl David Jungck Jürgen Behr Erich Stoelben Andrea Koch

Bacterial infections induce exacerbations in chronic lung diseases, e.g., chronic obstructive pulmonary disease (COPD), by enhancing airway inflammation. Exacerbations are frequently associated with right heart decompensation and accelerate disease progression. Endothelin receptor antagonists (ERAs) might have therapeutic potential as pulmonary vasodilators and anti-inflammatory agents, but uti...

Journal: :Molecules 2018
Chunjing Yang Longtai You Xingbin Yin Yi Liu Xin Leng Wenping Wang Na Sai Jian Ni

Heterophyllin B (HB), an active cyclic peptide, is a compound existing in the ethyl acetate extract of Pseudostellaria heterophylla (Miq.) Pax and exhibited the activity of inhibiting the production of NO and cytokines, such as IL-1β and IL-6, in LPS-stimulated RAW 264.7 macrophages. In addition, HB suppressed the production of ROS and the apoptosis induced by LPS in RAW 264.7 macrophages. The ...

Journal: :Infection and immunity 2006
Chiang W Lee Soumaya Bennouna Eric Y Denkers

Toxoplasma gondii-infected macrophages are blocked in production of the proinflammatory cytokines interleukin-12 (IL-12) and tumor necrosis factor alpha (TNF-alpha) upon activation with lipopolysaccharide (LPS). Here, we used pathway-focused cDNA arrays to identify additional T. gondii-regulated transcriptional responses. Parasite infection decreased 57 (inclusive of IL-12 and TNF-alpha) and in...

2015
Sayuri Okawa Kana Unuma Atsushi Yamada Toshihiko Aki Koichi Uemura

The involvement of the lung during the septic systemic inflammatory response elicited by administration of lipopolysaccharide (LPS) was investigated. Eight-week-old male Sprague-Dawley rats were injected i.p. with 15 mg/kg LPS. After 24 h, the lungs were excised to evaluate the cellular responses to LPS. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF) an...

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