Ascites is the most common complication of cirrhosis, and 60% of patients with compensated cirrhosis develop ascites within 10 years during the course of their disease [1]. Ascites only occurs when portal hypertension has developed [2] and is primarily related to an inability to excrete an adequate amount of sodium into urine, leading to a positive sodium balance. A large body of evidence sugge...

The mechanism of ascites formation has been a subject of interest for many years and remains a challenge to the investigator. In previous reports (1, 2) on 61 patients with cirrhosis of the liver, it was pointed out that those with ascites have lower values for serum albumin than do those without ascites and that the tendency to diuresis (and the loss of ascites) was correlated with a rise of t...

Various studies have investigated hepatic carcinoma cachexia, however, there is little published information regarding the effect of Chinese Medicine carcinoma cachexia. The present study was performed to investigate the effect of modified Chinese herbal compound jianpijiedu (MJPJD) on a mouse model of ascites‑induced hepatic carcinoma cachexia. C57BL/6 mice were randomized to five groups: Cont...

When cell suspensions of the Gardner lymphosarcoma were incubated with acetate-2-C14, ap preciable radioactivity was observed in the alpha carbon of free glycine (4). There are described be low experiments showing that the methyl carbon of acetate may also be utilized in the formation of free serine. The incorporation of radioactivity from labeled glucose into both amino acids and of labeled ri...

When cell suspensions of the Gardner lymphosarcoma were incubated with acetate-2-C14, ap preciable radioactivity was observed in the alpha carbon of free glycine (4). There are described be low experiments showing that the methyl carbon of acetate may also be utilized in the formation of free serine. The incorporation of radioactivity from labeled glucose into both amino acids and of labeled ri...

This study reports the effects of a short-term (60 min) low-dose (20 ng x kg(-1) x min(-1)) infusion of synthetic urodilatin (URO) in patients with liver cirrhosis. URO is a natriuretic peptide. A total of 15 cirrhotic patients with ascites and nine without ascites participated in a randomized, double-blind, placebo-controlled study in a crossover design. Renal hemodynamics were estimated by a ...

BACKGROUND/AIMS Hyperdynamic circulation, which is characterized by increased cardiac output (CO), normal or low arterial blood pressure (BP), and decreased systemic vascular resistance (SVR), occurs in patients with liver cirrhosis (LC). However, differences of hemodynamics between patients with alcoholic LC (ALC) and viral LC are not well understood. The aim of the present study was to compar...

We wish to report on a 28-year-old Sudanese woman who presented with a swelling in the left groin (Fig.1). The swelling had been present for a few months and was slowly increasing in size. It had previously been partially reducible, but was now irreducible. The patient was a fit young woman, with full flanks, a large spleen and moderate ascites. The large, irreducible left groin cystic mass tra...