background there is evidence in support of low bone density in young patients with disorders of phenylalanine metabolism; however, little is known about muscle and fat mass in these patients, especially in those with mild hyperphenylalaninemia (mhpa). objectives we aimed to evaluate body composition of children and adolescents with early-diagnosed disorders of phenylalanine metabolism. patients...

BACKGROUND Asthmatic patients taking low to moderate doses of inhaled topical corticosteroids have been shown to have lower bone density than those taking bronchodilators only. There is little information on bone density in asthmatic patients taking high dose inhaled corticosteroids. METHODS Bone mass was studied in three age matched groups of asthmatic patients. These comprised: 17 asthmatic...

the intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. to clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (ldl) to oxidative modification. in this study, “lycopene” was added to plasma and incubated...

Patients with chronic kidney disease-mineral and bone disorder (CKD-MBD) have a high risk of bone fracture because of low bone mineral density and poor bone quality. Osteoporosis also features low bone mass, disarranged microarchitecture, and skeletal fragility, and differentiating between osteoporosis and CKD-MBD in low bone mineral density is a challenge and usually achieved by bone biopsy. B...