Deletions of loci on chromosome lip have been found frequently in several malignant tumors including gliomas, suggesting the presence of tumor suppressor genes. We analyzed 38 gliomas [26 malignant gliomas (grades III and IV) and 12 less malignant gliomas (grades I and II)] for loss of heterozygosity using microsatellite sequences on lip as polymor phic markers. Loss of heterozygosity was found...
