Sleep deprivation disrupts hippocampal function and plasticity. In particular, long-term memory consolidation is impaired by sleep deprivation, suggesting that a specific critical period exists following learning during which sleep is necessary. To elucidate the impact of sleep deprivation on long-term memory consolidation and synaptic plasticity, long-term memory was assessed when mice were sl...

The objective of this review is to sum up the literature regarding the management of patients with chronic obstructive pulmonary disease (COPD) after hospitalization for an acute exacerbation. Guidelines recommend a follow-up 4-6 weeks after hospitalization to assess coping strategies, inhaler technique, the need for long-term oxygen therapy and the measurement of FEV(1). This review discusses ...

A validity test was conducted to determine how care level-based nurse-to-resident ratios compare with actual daily care times per resident in Germany. Stability across different long-term care facilities was tested. Care level-based nurse-to-resident ratios were compared with the standard minimum nurse-to-resident ratios. Levels of care are determined by classification authorities in long-term ...

Long-term care demographic and industry trends challenge provision of effective care and infection prevention. A systematic review was conducted to identify and evaluate cost estimates reported in the scientific literature of structure and processes intended to prevent infection among residents and staff of long-term care facilities (LTCFs). The small volume of publications regarding cost of in...

The need for long-term care (LTC) represents a “new social risk,” one that overlaps with and complements systems of care that pre-date such programs, complicating LTC program design. This commentary expands on Ikegami’s discussion of how these structural factors must be accommodated, as well as historical and cultural factors that influence public expectations of such a...

Long-term potentiation (LTP) is a persistent increase in synaptic transmission that is thought to contribute to a variety of adaptive processes including learning and memory. Although learning is known to undergo circannual variations, it is not known whether LTP undergoes similar changes despite the importance of LTP in learning and memory. Here we report that synapses in the CNS of the medici...

OBJECTIVE Taiwan's health-care system allows patients to utilize specialty services without referrals by primary care providers. This discontinuity of care may lead to increases in future hospitalizations. This study aims to determine whether the discontinuity of care is associated with the risk of hospitalization. DESIGN A secondary data analysis based on a claim data of a nationally represe...

background: patellar mal tracking is responsible for pain and disability in patellofemoral pain syndrome (pfps). patellar kinesio taping may have different effects on short and long term usage. the aim of this study is to compare the effect of short term and long term patellar kinesio taping in patellar position on women with patellofemoral pain syndrome using magnetic resonance imaging (mri). ...

objective: administration of amoxicillin and metronidazole along with scaling and root planning (srp) is an effective adjunctive therapy for chronic periodontitis. studies have shown that administration of azithromycin is also effective for treatment of chronic periodontitis. this study aimed to compare the effect of short-term and long-term azithromycin regimen with amoxicillin and metronidazo...

Repeated application of manures to agricultural soils could cause the accumulation of phosphorus (P) in soils. However, it is unclear if manure P can behave similar to P in soluble fertilizers in accumulation Olsen-P (0.5 mol L-1 NaHCO3 at pH 8.5) in soils. A long-term wheat-maize rotation experiment was conducted to investigate the effects of repeated application of manures on P accumulation i...