نتایج جستجو برای: locus ceruleus
تعداد نتایج: 66544 فیلتر نتایج به سال:
We have developed a dissociated primary cell culture of noradrenergic neurons from the locus ceruleus of postnatal (1- to 5-d-old) mice or rats. Slices of the brain stem were made on a Vibratome. Then the region of locus ceruleus, which was identified by observing the slices under a dissecting microscope, was dissected out from the slices. The removed fragments of brain slices were dissociated ...
Norepinephrine, acting through -adrenergic receptors, is implicated in mammalian memory. In in vitro and in vivo studies, norepinephrine produces potentiation of the perforant path– dentate gyrus evoked potential; however, the duration and dynamics of norepinephrine-induced potentiation have not been explored over extended time periods. To characterize the long-term effects of norepinephrine on...
cal – chest XP and CT revealed no lesion affecting the recurrent and/or vagus nerves. The family’s consent to perform tracheotomy was not obtained. At the age of 89, he was admitted to our hospital with pyrexia. On admission, neurological examination revealed new findings including right-sided dominant rigidity and Myerson’s sign. Resting tremor was absent. He showed severe dementia (MMSE 0/30)...
Imber AN, Putnam RW. Postnatal development and activation of L-type Ca currents in locus ceruleus neurons: implications for a role for Ca in central chemosensitivity. J Appl Physiol 112: 1715–1726, 2012. First published March 8, 2012; doi:10.1152/japplphysiol.01585.2011.— Little is known about the role of Ca in central chemosensitive signaling. We use electrophysiology to examine the chemosensi...
Corticotropin-releasing factor (CRF) administered intracerebroventricularly (i.c.v.) activates noradrenergic locus coeruleus (LC) neurons of halothane-anesthetized and unanesthetized rats. This study used a technique for microinfusing CRF into the LC from calibrated micropipettes to characterize and quantify the effects of locally administered CRF on LC discharge in halothane-anesthetized rats....
Slow, controlled breathing has been used for centuries to promote mental calming, and it is used clinically to suppress excessive arousal such as panic attacks. However, the physiological and neural basis of the relationship between breathing and higher-order brain activity is unknown. We found a neuronal subpopulation in the mouse preBötzinger complex (preBötC), the primary breathing rhythm ge...
The localization of orexin neuropeptides in the lateral hypothalamus has focused interest on their role in ingestion. The orexigenic neurones in the lateral hypothalamus, however, project widely in the brain, and thus the physiological role of orexins is likely to be complex. Here we describe an investigation of the action of orexin A in modulating the arousal state of rats by using a combinati...
Value-based decisions optimize the relation of costs and benefits. Costs and benefits confer not only value but also salience, which may influence decision making through attentional mechanisms. However, the computational and neurobiological role of salience in value-based decisions remains elusive. Here we develop and contrast two formal concepts of salience for value-based choices involving c...
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