Chondroma is the most common neoplasia of the hand. Histologically, it consists of lobules of normal-appearing hyaline cartilage showing a lobular arrangement. To the best of our knowledge, this is the first reported case of chondroma of the hand in which, interestingly, osteoid production was observed.

The localization of Australia antigen in the liver by the fluorescent antibody technique (direct method) has been studied. Specific fluorescence was observed in the cytoplasm of liver cells. Two distribution patterns of fluorescent-positive cells, namely, a diffuse fluorescence in the liver lobules and a spotty distribution of fluorescent-positive cells, were observed.

Sarcoid granulomata were found incidentally in the mammary lobules adjacent to an excised fibroadenoma in a case of sarcoidosis of the breast. The diagnosis of sarcoidosis was established by the radiological finding of bilateral hilar lymphadenopathy, raised concentrations of serum angiotensin converting enzyme and lysozyme, and, finally, by a positive Kveim test.

The magnetoencephalographic signal was collected in a visually guided response-finger selection GO/NOGO task. The minimum norm distributed source analysis identified the sources in bilateral superior parietal lobules (SPL), with stronger activity for contralateral finger movement. Our results suggest that the human SPL plays a role in the spatial selection in a visuomotor task similar to that i...

Spinocerebellar ataxia type 17 (SCA17) is a rare autosomal dominant neurodegenerative disorder characterized by progressive cerebellar ataxia but also a broad spectrum of other neuropsychiatric signs. As anatomical and structural studies have shown severe cerebellar atrophy in SCA17 and a differentiation of the human cerebellum into an anterior sensorimotor and posterior cognitive/emotional par...

The substratum for many cell types is the extracellular matrix (ECM). However, the ECM is not only a physical supporting framework for the cells, but may be linked to the cells by molecules which are intimately associated with the plasma membrane. Changes in cell-ECM interactions modify cell shape, motility, and proliferation and, because the ECM distributes over many cells, can integrate these...