The administration of aqueous thyme extract was investigated for its hepatoprotective effect in rabbits with acute liver injury induced by a single i.p. injection of cisplatin (6.5 mg/kg). Aqueous thyme extract treatment (500 mg/kg/day, orally) was applied for 7 consecutive days, starting 4 days before cisplatin administration. Aqueous thyme extract significantly reduced serum levels of liver e...

the methanolic extract of leaves of turnera ulmifolia l was evaluated for its effect on blood glucose in alloxan-induced diabetic and euglycemic rats. the extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. glibenclamide (10 mg/kg, p.o.) was used as standard for control group. in euglycemic rat, extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. extrac...

Objective(s): Mesenchyme is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm. Recently, mesenchymal stem cells (MSCs), as adult stem cells (ASCs) able to divide into a variety of different cells, are of utmost importance for stem cell research. In this research, ability of the liver extract to induce differentiation of rat derived omentum tissue mesenchyma...

the present study was conducted to evaluate the protective effect of methanolic leaf extract of caesalpinia bonduc (l.) on gentamicin-induced hepatotoxicity and nephrotoxicity in rats . a control group (saline, group i, n = 6) was compared with rats administrated 80 mg/kg gentamicin, once daily for 7 days (groups ii, iii and iv). the effect of methanolic leaf extract of caesalpinia bonduc (grou...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

Homalium letestui Pellegr (Flacourtiaceae) is used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases and Yorubas of western Nigeria as an antidote. The hepatoprotective effect of the stem extract (200-600 mg/kg) was evaluated by the assay of liver function parameters, namely total and direct bilirubin, serum protein and albumin, tot...

In order to assess the potency of aqueous stem bark extract of Khaya senegalensis (KS) against liver diseases, serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) were assayed in rats treated with two (2) different doses of the extract after the induction of liver damage in the rats using carbon tetrachloride, CCl4. The rats treated with a daily dose of...