We report a case of renal cell carcinoma in which up to 32% of the abnormally increased alkaline phosphatase activity in serum was contributed by a variant alkaline phosphatase originating in the primary tumor and its secondary deposits. The variant enzyme was probably an altered form of normal renal alkaline phosphatase. The rest of the alkaline phosphatase activity in the serum was of hepatic...

A 49-year-old woman presented in fulminant hepatic failure. The ECG showed dramatic ST-segment elevation, suggesting diffuse myocardial injury. However, echocardiography, creatine phosphokinase enzyme determinations, and examination of the heart at autopsy (six days later) failed to demonstrate any physiologic, anatomic, or histologic evidence of abnormality. The appearance of ST-segment elevat...

A case of malignant schwannoma of the sciatic nerve is described associated with hepatic dysfunction in the absence of hepatic metastases. An elevated serum alkaline phosphatase activity was present with an isoenzyme pattern indicating hepatic involvement. These abnormalities disappeared after extirpation of the tumour. The patient is well, with no evidence of metastases, over two years later. ...

A case of agenesis or aplasia of the right lung, in a cyanosed neonate, exceptionally associated with a 'vascular ring' abnormality produced by a right aortic arch, an aberrant left subclavian artery, and a patent ductus arteriosus, is reported. The presence of an abnormal lobe of the liver, projecting together with small gut and a subhepatic caecum into the right hemithorax, caused mediastinal...

A detailed description of the types of Gaucher’s is beyond the scope of this paper. Classicall3~ three types are described. Type 2, acute neurologic, is usually fatal in infancy with an average age at death of 18 months.2 Type 3, chronic neurologic, usually presents during childhood with diffuse progressive neurologic symptoms. There is a distinct subgroup whose sole neurological defect is a la...

abstract : before initiating any endodontic therapy, probability of extra canals should be considered. the incidence of three canals in mandibular second premolar has been reported to be 0.46-0.5%. the present report describes nonsurgical endodontic treatment of three mandibular second premolars with three canals. in these cases, three orifices were located in mesiobuccal, distobuccal and lingu...

by increasing number of vessels. salivary gland tumors are uncommon and their overall incidence is about 3 per 100000 per year. salivary gland hemangioma makes up 1 % of all salivary gland tumors. trismus resulting from parotid hemangioma is so rare. the patient was a 6-month-old boy with a huge lesion in his right parotid who referred to shahid sadoughi hospital of yazd, iran. the lesion appea...

over the right chest wall, not obviously associated with any clinical abnormality. Ten days after admission, oedema of the face became apparent. Emination revealed a swollen right arm, a much enlarged and tender right breast, associated with dilated veins in the chest wall, and non-pulsatile distension of the neck veins. A diagnosis of superior vena caval obstruction was made. The liver was enl...

Application of a small dose of glyceryl trinitrate paste (0.25 in) resulted in severe left ventricular dysfunction with the appearance of pulsus alternans in a patient with alcoholic cardiomyopathy. The echocardiogram showed a reduction in the amplitude and velocity of motion of the left ventricular posterior wall on alternate beats. Leg elevation promptly reversed the pulsus alternans, and the...