Since the introduction of our local manufacturing of terfenadine, we have observed and expressed our concern about a small but increasing number of serious ventricular arrhythmias associated with the use of this non sedating antihistamine. In January 1997 a case of torsade de pointes ventricular tachycardia was detected in a previously healthy woman taking terfenadine with erythromycin. El...

This Article, with a descriptive-analytical method and phenomenological approach, tries to explain the motives, solutions, and achievements of Dārā Shukūh (fl. 11th century AH) in Muslim-Hindu relations. It will also describe his ways of interaction and explain some negative reactions against his policies. Dārā Shukūh’s main motives were his special family upbringing, his chivalrous ...

Background: Medication interactions are associated with various unwanted adverse drug reactions. Medication Reconciliation involves a process in which a complete list of patient's previously prescribed medications are recorded and subsequently evaluated within the context of concomitantly prescribed medications and present medical condition during the hospitalization. Method: Medical records ...

Background: Medication interactions are associated with various unwanted adverse drug reactions. Medication Reconciliation involves a process in which a complete list of patient's previously prescribed medications are recorded and subsequently evaluated within the context of concomitantly prescribed medications and present medical condition during the hospitalization. Method: Medical records ...

there are two different co-expression systems including bicistronic; dual-vector or two-promoter to express two different genes simultaneously and also to study protein-protein interactions. bicistronic system has disadvantages e.g. compared with two-promoter system. in this paper, a simple method based on spliced overlap extension by polymerase chain reaction (soe-pcr) technique was demonstrat...

the energy minima of systems made of an alanine molecule, a lithium cation and a various number of watermolecules have been determined with the help of quantum mechanical computations at the b3lyp densityfunctional theory level of computation and the standard 6-311++g (d,p) basis set. several structures, close inenergy are found and the presence of one or two water molecules around the cation m...

the entomopathogenic-fungus-life cycle is associated with the synthesis and secretion of a number of toxic metabolites, including extracellular enzymes and the low-molecular weight compound (toxin). the potential for a successful pathogen relies on the ability to overcome the various host-defence systems. interaction between the fungus, tolypocla-dium (deuteromycetes), its secondary metabolite,...

fe49co33ni18 nanowire arrays (175 nm in diameter and lengths ranging from 5 to 32μm) were fabricated into nanopores of hard-anodized aluminum oxide templates using pulsed ac electrodeposition technique. hysteresis loop measurements indicated that increasing the length decreases coercivity and squareness values (from 274 oe and 0.58 to200 oe and 0.105, respectively), indicating the increase in m...

Investigations of microbial ecology and diversity have been greatly enhanced by the application of culture-independent techniques. One such approach, metagenomics, involves sample collections from soil, water, and other environments. Extracted nucleic acids from bulk environmental samples are sequenced and analyzed, which allows microbial interactions to be inferred on the basis of bioinformati...