the non-enzymatic glycation of low density lipoprotein (ldl) is a naturally occurring chemical modification of apolipoprotein b as a result of condensation between lysine residues and glucose. glycated ldl is poorly recognized by ldl receptors and initiates different processes that can be considered proatherogenic. thus, ldl glycation may contribute in the increased atherosclerotic risk of pati...

objective(s):resveratrol (res) is a polyphenol compound that has been shown a promising cardioprotective effect. however, some reports have yielded conflicting findings. herein, we investigated the anti-atherosclerotic effects of res in apolipoprotein e (apo e)-deficient mice on a high cholesterol diet. materials and methods: firstly, atherosclerosis was induced by feeding a high cholesterol di...

background: coronary artery disease (cad) is one of the leading causes of death and disability around the world. interaction between genetic and environmental factors determines susceptibility of an individual to develop coronary artery disease . lipoprotein lipase (lpl) play an important role in the metabolism of hdl-c ( high density lipoprotein cholesterol ), ldl-c (low density lipoprotein ch...

background: this study was done to test the notion that opium can reduce serum lipids and decrease the risk of ischemic heart disease (ihd) in opium addicts; we made a comparison between the lipid profiles of opium addicts and non-addicts.   methods: in this study, we compared 100 male opium addicts (according to the icd-10 criteria) who had referred to addiction treatment centers with 75 healt...

abstract introduction: liposuction is a surgical procedure effective in reducing body fat, with growing application in conjunction with diet and exercise therapy in the treatment of obesity. in view of the positive effect of weight reduction on cardiovascular disease (cvd) risk factors, such as body mass index (bmi), waist circumference (wc), waist-to-hip ratio (whr), systolic and diastolic pre...

background : many types of cancer cells require a supply of fatty acids (fa) for growth and survival, lpl, in the presence of triglyceride-rich lipoproteins, accelerates the growth of these cells. recent evidence shows that lpl plays important roles in inflammation and obesity, implies that it is an appropriate general target for chemo preventive and chemotherapeutic agents. thus, we reported l...

conclusions in a current study based on increasing maternal age, the hdl-c level in cord blood was decreased which is an independent risk factor for cvds in adulthood. results a statistically significant negative correlation was observed between cord blood hdl-c and maternal age (r = -0.18, p <0.01). there was no relationship between other lipids and lipoproteins with maternal age. our findings...