نتایج جستجو برای: lipogenic enzymes
تعداد نتایج: 127565 فیلتر نتایج به سال:
High-fat diets (HFD) promote the development of both obesity and fatty liver disease through the up-regulation of hepatic lipogenesis. Insulin resistance, a hallmark of both conditions, causes dysfunctional fuel partitioning and increases in lipogenesis. Recent work has demonstrated that systemic insulin resistance occurs in as little as the first 72 hours of an HFD, suggesting the potential fo...
BACKGROUND Loss of the endosulfatase HSulf-1 is common in ovarian cancer, upregulates heparin binding growth factor signaling and potentiates tumorigenesis and angiogenesis. However, metabolic differences between isogenic cells with and without HSulf-1 have not been characterized upon HSulf-1 suppression in vitro. Since growth factor signaling is closely tied to metabolic alterations, we determ...
Endurance exercise (EE) leads to beneficial alterations in skeletal muscle lipid metabolism in overweight and obese individuals, however the mechanisms of these improvements are poorly understood. The primary goal of the current investigation was to test the hypothesis that long-term EE training (six months) leads to alterations in the mRNA abundance of key lipid metabolism enzymes in skeletal ...
The hindlimb-suspended rat was used as animal model to investigate the effects induced by immobilization of the skeletal muscle in the expression of the genes encoding hepatic lipogenic enzymes. Following a 14-day period of immobilization, rats were injected intraperitoneally with radioactive acetate, and the labeling of hepatic lipids and cholesterol was evaluated 15 min after the isotope inje...
Glycerol is the by-product of biodiesel production and its utilisation in fish feed has recently gained relevance. As an important metabolic intermediate structural component triacylglycerol (TAG), it still unclear whether supplementation affects lipid and/or deposition different tissues. Accordingly, a set studies was aimed to evaluate how increasing levels dietary glycerol (0, 2.5 5%) affect ...
I . Adult male Japanese quail (Coturnix Coturnix Japonica) were overfed at different intensities during varying periods: (I) by gradually increasing the daily amount of food up to twice the control level in a period of 1 1 d and keeping this level constant during the subsequent 12 d period (prolonged overfeeding); ( 2 ) by gradually increasing the daily amount of food up to approximately twice ...
The activities of phosphoenolpyruvate carboxykinase, ;malic enzyme', citrate-cleavage enzyme and glucose 6-phosphate dehydrogenase were assayed in homogenates of rumen mucosa, liver and adipose tissue of cattle. Rumen mucosa cytoplasm contained activities of ;malic enzyme' approximately sevenfold those of phosphoenolpyruvate carboxykinase, suggesting that the conversion of propionate into lacta...
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