Background and objectives: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease caused by the accumulation of large amounts of fat in the hepatocytes. Given that atorvastatin is effective for treatment of NAFLD, the present study investigated effects of high-fat/fructose diet (HFFD) with atorvastatin on liver enzymes and lipid profile in a NAFLD rat model. Methods: Thirty-two m...

Cerebrotendinous xanthomatosis (CTX) is an autosomal recessive disorder caused by pathogenic variants in CYP27A1, leading to a deficiency sterol 27-hydroxylase. This defect results the accumulation of cholestanol and bile alcohols various tissues, including brain, tendons peripheral nerves. We conducted this review evaluate lipid profile abnormalities patients with CTX. A search was PubMed, Emb...

Objective: Diabetes Mellitus (DM) is one of the leading causes of death, illness, and economic loss in the world. The present study was attempted to evaluate extract of Foeniculum vulgare (fennel) on lipid profile, lipid peroxidation and activities of amino transferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: The effects of daily oral administration of...

The chorea-acanthocytosis syndrome (CHAC) is a rare disorder beginning in late adolescent or adult life in association with acanthocytosis, a normal lipid profile and characterized by progressive neurological disease. The inheritance is usually autosomal recessive, although apparent sporadic and autosomal dominant instances are also known. We report here a young man who presented with choreo-at...

conclusions twelve weeks of two grams of ginger supplementation showed beneficial effects on some nafld characteristics. further studies are recommended to assess the long-term supplementation effects. results ginger supplementation resulted in a significant reduction in alanine aminotransferase, γ-glutamyl transferase, inflammatory cytokines, as well as the insulin resistance index and hepatic...

Introduction: Exercise training and omega 3 supplements play an important role in modulating the levels of oxidative and inflammatory mediators. The present study conducted aimed to investigate the effects of aerobic training and omega-3 supplementation on the levels of oxidative (MDA) and inflammatory (CRP) mediators and lipid profile in overweight and obese women. Materials and Methods: The ...

Objective: The effect of herbal medicine is more useful than synthetic medicines. The present research paper aims to show the effects of leaves extracts of Zizyphus Spina Christi (ZSC) on lipid profile, lipid peroxidation and activities of aminotransferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: Fifty six male rats weighing 150-200 gm were included in t...

BACKGROUND Dyslipidemia occurring in diabetic patients, play a critical role in acceleration of macrovascular atherosclerosis and contribute to the excess risk of CVD. Keeping in view the prevalence and increased risk of cardiovascular disease in diabetes, it is becoming necessary to diagnose prediabetic individuals and assess their lipid profile and prevent them from developing overt diabetes ...