OBJECTIVEdTo study the effects of high-protein versus high-carbohydrate diets on various metabolic end points (glucoregulation, oxidative stress [dichlorofluorescein], lipid peroxidation [malondialdehyde], proinflammatory cytokines [tumor necrosis factor-a and interleukin-6], adipokines, and resting energy expenditure [REE]) with high protein–low carbohydrate (HP) and high carbohydrate–low prot...

Objective: The effect of herbal medicine is more useful than synthetic medicines. The present research paper aims to show the effects of leaves extracts of Zizyphus Spina Christi (ZSC) on lipid profile, lipid peroxidation and activities of aminotransferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: Fifty six male rats weighing 150-200 gm were included in t...

In the present study, we have evaluated the protective effect of vitamin E (VE) against adriamycin (AD) and cyclophosphamide (CP) induced genotoxicity using chromosome aberration and micronucleus assays in Wistar rat bone marrow cells. The level of lipid peroxidation product malondialdehyde, the activity of antioxidant enzymes

BACKGROUND Lipid peroxidation may be important in the pathogenesis of atherosclerosis, particularly in its earliest stages. Evidence predominantly from in vitro studies suggests that antioxidant vitamins can prevent lipid peroxidation and that vitamin C and vitamin E have synergistic effects. However, in vivo evidence in support of these hypotheses is sparse. OBJECTIVE The objective was to de...

OBJECTIVE This study examined the relationship between cellular glutathione and vitamin E concentrations and the effect of vitamin E (alpha-tocopherol) supplementation on glutathione and lipid peroxidation product concentrations in the erythrocytes of type 1 diabetic patients. RESEARCH DESIGN AND METHODS We obtained written informed consent to participate in this study from diabetic patients ...

A drug may cause alteration in blood-lipid profile and induce lipid peroxidation phenomena on administration in the body. Antioxidant may play beneficial role to control the negative alteration in lipid profile and lipid peroxidation. In view of this context, the present in vivo study was carried out to evaluate the role of ascorbic acid as antioxidant on netilmicin-induced alteration of blood ...

Free radicals are implicated in several diseases of prematurity. The study aimed to correlate plasma antioxidants levels and lipid peroxidation between maternal and cord blood in normal and preterm deliveries. Superoxide dismutase (SOD), Reduced Glutathione (GSH) and Uric acid were the measured antioxidants while Malondialdehyde (MDA) was an index of lipid peroxidation. 32 mothers who delivered...

Osteoarthritis (OA) affects a large segment of the aging population and is a major cause of pain and disability. At present, there is no specific treatment available to prevent or retard the cartilage destruction that occurs in OA. Recently, glucosamine sulfate has received attention as a putative agent that may retard cartilage degradation in OA. The precise mechanism of action of glucosamine ...

OBJECTIVES Previous research on a group of workers occupationally exposed to styrene, ethylene glycol, toluene, p-xylene and their mixture showed elevated levels of the main products of lipid peroxidation: malondialdehyde and 4-hydroxynonenal (MDA+,4-HNE) in plasma [1]. Moreover, an earlier in vitro study indicated a synergistic interaction between styrene and ethylene glycol on lipid peroxidat...