Selective autophagy contributes to cellular homeostasis by delivering harmful material into the lysosomal system for degradation via vesicular intermediates referred to as autophagosomes. The cytoplasm-to-vacuole targeting pathway is a variant of selective autophagy in Saccharomyces cerevisiae during which hydrolases such as prApe1 are transported into the vacuole. In general, selectivity is ac...

We prove local well-posedness results for the semi-linear wave equation for data in H , 0 < < n?3 2(n?1) , extending the previously known results for this problem. The improvement comes from an introduction of a two-scale Lebesgue space X r;p k .

In order to investigate the effect of linearized process on the adsorption equilibrium isotherms of methylene blue from solutions onto rice husk, the experimental data were fitted to the Langmuir isotherm equations by using five different types of linear expression. The adsorption equilibrium constant related to the affinity of the binding sites and energy of adsorption (KL ) and maximum adsorp...

By the linear algebraic representation of Petri nets, Desel introduced regularity property (Desel, 1992). Regularity implies a sufficient condition for a Petri net to be live and bounded. All the conditions checking the regularity of a Petri net are decidable in polynomial time in the size of a net (Desel and Esparza, 1995). This paper proves that regularity, liveness and boundedness can be pre...

The present study explores the seismic performance and expected structural damage in reinforced concrete (RC) frames with progressively increasing in-plan in-height non-regularity. To this aim, four three-dimensional (3D) buildings characterised by different regularity levels are taken into account. structures subjected to input consisting of unscaled real ground motion records, non-linear dyna...

Macroautophagy was initially considered to be a nonselective process for bulk breakdown of cytosolic material. However, recent evidence points toward a selective mode of autophagy mediated by the so-called selective autophagy receptors (SARs). SARs act by recognizing and sorting diverse cargo substrates (e.g., proteins, organelles, pathogens) to the autophagic machinery. Known SARs are characte...