نتایج جستجو برای: like 2 rs7903146

تعداد نتایج: 3019731  

Journal: :Human reproduction update 2013
Cuilin Zhang Wei Bao Ying Rong Huixia Yang Katherine Bowers Edwina Yeung Michele Kiely

BACKGROUND Several studies have examined associations between genetic variants and the risk of gestational diabetes mellitus (GDM). However, inferences from these studies were often hindered by limited statistical power and conflicting results. We aimed to systematically review and quantitatively summarize the association of commonly studied single nucleotide polymorphisms (SNPs) with GDM risk ...

Journal: :Diabetes 2009
Yasuharu Tabara Haruhiko Osawa Ryuichi Kawamoto Hiroshi Onuma Ikki Shimizu Tetsuro Miki Katsuhiko Kohara Hideichi Makino

OBJECTIVE The present study was conducted to confirm possible associations between candidate genes from genome-wide association studies and type 2 diabetes in Japanese diabetic patients and a community-based general population. A total of 11 previously reported single-nucleotide polymorphisms (SNPs) from the TCF7L2, CDKAL1, HHEX, IGF2BP2, CDKN2A/B, SLC30A8, and KCNJ11 genes were analyzed. RES...

2007
Ruth J.F. Loos Paul W. Franks Richard W. Francis Inês Barroso Fiona M. Gribble David B. Savage Ken K. Ong Stephen O’Rahilly Nicholas J. Wareham

Rapidly accumulating evidence shows that common T-cell transcription factor (TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown mechanisms. We examined the association between four TCF7L2 single nucleotide polymorphisms (SNPs), including rs7903146, and measures of insulin sensitivity and insulin secretion in 1,697 Europid men and women of the population-based MRC (Medical Rese...

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2017

Journal: :The Journal of clinical investigation 1983
W L Isley L E Underwood D R Clemmons

Dietary components responsible for the regulation of somatomedin-C in humans were assessed in five adult volunteers of normal weight who were fasted for 5 d on three occasions, then refed three diets of differing composition. The serum somatomedin-C decreased from a mean prefasting value of 1.85 +/- 0.39 U/ml (+/- 1 SD) to 0.67 +/- 0.16 U/ml at the end of fasting (P less than 0.005). After refe...

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