Licorice is an important traditional Chinese medicine with clinical and industrial applications. Genetic resources of licorice are insufficient for analysis of molecular biology and genetic functions; as such, transcriptome sequencing must be conducted for functional characterization and development of molecular markers. In this study, transcriptome sequencing on the Illumina HiSeq 2500 sequenc...

INTRODUCTION A 49-year-old woman was admitted to our hospital because of thunderclap headache and blurred vision. At the time of presentation, her blood pressure was 219/100 mmHg, her arterial pH was 7.64 and her potassium level was 2.7 mM/l. METHODS The combination of sequential computed tomography (CT) and the triad of hypertension, hypokalemia and metabolic alkalosis in this patient sugges...

Pressurized hot water extraction (PHWE) is a very useful technique for recovering bioactive molecules from natural materials using subcritical compressed liquid water in the temperature range of 50–150 ◦C. A novel process has been developed for making a natural sweetener from licorice (Glycyrrhiza glabra) roots involving selective chemical reaction and easy separation, for recovering mono-ammon...

BACKGROUND Burn is still one of the most devastating injuries in emergency medicine while improvements in wound healing knowledge and technology have resulted into development of new dressings. This study was undertaken to evaluate the healing effect of licorice in Pseudomonas aeruginosa infected burn wounds of experimental rat model. METHODS One hundred and twenty female Sprague-Dawley rats...

The present study was undertaken to determine the anti-ulcer and antioxidant potential of GutGard, a standardized extract of Glycyrrhiza glabra commonly known as licorice. Effect of various doses (12.5, 25, and 50 mg/kg, po) of GutGard was studied on gastric ulcers in pylorus ligation-, cold-restraint stress- and indomethacin induced gastric mucosal injury in rats. Anti-ulcer activity was evalu...

As the development of the natural medicine, the glycyrrhizin extracted from the licorice root was found to have potential therapeutic value in the treatment of several diseases, especially available for anti-SARS virus . Therefore, the purpose of this work was to find an optimal method to extract and refine the glycyrrhizin. In this work, the extraction of glycyrrhizin by means of organic solve...

Licorice (roots and stolons of Glycyrrhiza plants, Leguminosae) is a well-known natural sweetener, and its sweet constituent is an oleanane-type triterpene saponin, glycyrrhizin. Cultured cells of G. glabra do not produce glycyrrhizin, but produce two structurally different triterpenoid constituents, betulinic acid and soyasaponins. Both glycyrrhizin and soyasaponins are oleanane-type triterpen...

introduction: glycyrrhiza glabra (licorice) root, a member of the pea family has been used since ancient times as both food and medicine. licorice has been used as an antioxidant, antimicrobial and anti inflammatory in researches .extraction of this medical plant is used as the basis of anti-ulcer medicine for treatment of peptic ulcer. patients and methods: in the present study, licorice decoc...

Overexposure to glucocorticoids may link prenatal adversity with detrimental outcomes in later life. Glycyrrhiza, a natural constituent of licorice, inhibits placental 11-beta-hydroxysteroid dehydrogenase type 2, the feto-placental "barrier" to higher maternal levels of cortisol. The authors studied whether prenatal exposure to glycyrrhiza in licorice exerts detrimental effects on cognitive per...

Hadi Darvishi Khezri, MSc Thalassemia Research Center Hemoglobinopathy Institute, Booali Sina Hospital Pasdaran Boulevard, Sari, Iran [email protected] © 2014 S. Karger AG, Freiburg 1661–4119/14/0216–0418$39.50/0 Coronary artery bypass graft (CABG) surgery is one of the most commonly performed invasive procedures worldwide [1, 2]. Since the introduction of cardiopulmonary bypass (CPB), t...