ZNF480 has not yet attracted attention in the study of malignant tumors. Therefore, this attempts to explain significance pathological process lower-grade gliomas (LGG) based on large-scale samples from public database sources and vitro experiments. Reverse transcription quantitative real-time polymerase chain reaction immunohistochemistry confirmed that was highly expressed at both mRNA protei...

Aging is associated with a decline in many components of the immune system (immunosenescence). Probiotics may improve response older people. The objective was to determine effect combination two probiotic organisms [ Lacticaseibacillus (previously known as Lactobacillus ) rhamnosus GG (LGG) and Bifidobacterium animalis subsp. lactis , BB-12 (BB-12)] on range biomarkers measured blood people res...

The molecular nature of platelet receptors for quinineand quinidine-dependent antiplatelet antibodies (Q.Ab and Qd.Ab) was studied by immunoblotting. One Q.Ab caused quinine-dependent lgG binding to platelet proteins with molecular weights (mol wts) of 1 74 Kd and 93 Kd and another to only a 93-Kd protein. A third Q.Ab caused binding to 1 74-. 140-. 93-. and 57-Kd proteins, while a fourth Q.Ab ...

High-dose intravenous gammaglobulin (lVlgG) was given to 1 2 children and adults with chronic idiopathic thrombocytopenic purpura (ITP) to avoid splenectomy or because they either failed to respond to or required maintenance with high doses of steroids and/or immunosuppressives. The average platelet count increase to initial therapy was 239.5OO/ zl (range 23.000-790,000). A concomitant lgG Fc r...

We report the immunochemical characterization of a new platelet-specific alloantigen detected using an lgG antibody isolated from the serum of a patient with posttransfusion purpura (PTP). In indirect immunoprecipitation experiments, the antibody, termed anti Leka, predominantly precipitated glycoprotein (GP) llb from Triton X-100 lysates of normal human platelets. In an immunoblot procedure, w...

In this paper, we present a general framework for supervised classi cation. This framework provides methods like boosting and only needs the de nition of a generalisation operator called lgg. For sequence classi cation tasks, lgg is a learner that only uses positive examples. We show that grammatical inference has already de ned such learners for automata classes like reversible automata or k-T...

We report the immunochemical characterization of a new platelet-specific alloantigen detected using an lgG antibody isolated from the serum of a patient with posttransfusion purpura (PTP). In indirect immunoprecipitation experiments, the antibody, termed anti Leka, predominantly precipitated glycoprotein (GP) llb from Triton X-100 lysates of normal human platelets. In an immunoblot procedure, w...

Amgen, Inc. Comparative Biology and Safety Science Laboratory, Cambridge, MA 02142, USA: TJL Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA: TJL, LGG Amgen, Inc. Comparative Biology and Safety Science Laboratory, Thousand Oaks, CA 91320, USA: PC, RTD, HH, HM, CA Center for Gynepathology Research, Massachusetts Institute of Technology, Cambr...

In evaluating the therapeutic efficacy of gammaglobulin preparations in patients with agammaglobulinemia, opsonic activity of patients' sera in terms of oxygen consumption capacity of normal leukocytes is advocated as a useful index. Although the serum lgG level is a commonly used indicator, its determination alone was found out not always to reflect antibody levels in such sera. The method des...

The molecular nature of platelet receptors for quinineand quinidine-dependent antiplatelet antibodies (Q.Ab and Qd.Ab) was studied by immunoblotting. One Q.Ab caused quinine-dependent lgG binding to platelet proteins with molecular weights (mol wts) of 1 74 Kd and 93 Kd and another to only a 93-Kd protein. A third Q.Ab caused binding to 1 74-. 140-. 93-. and 57-Kd proteins, while a fourth Q.Ab ...