background and objectives: presence of methicillin and multidrug resistance has associated coagulase negative staphylococci (cns) with high morbidity and mortality worldwide. the present study was carried out to study the susceptibility pattern of cns to various antimicrobial agents and to determine the prevalence of cns methicillin resistance in our hospital setting. materials and methods: a t...

BACKGROUND AND AIMS Enterococci are among resistant microorganisms to antibiotics and are responsible for some of acute gingival infections. This study aimed at molecular evaluation of gentamicin-resistant enterococcus species and determining the resistance genes. MATERIALS AND METHODS Clinical samples were cultured on BHI medium and enterococci were isolated by specific methods and antibiogr...

BACKGROUND/AIM In some clinical forms of human Campylobacter infections, such as prolonged diarrhea or associated with postinfections sequels, antibacterial treatment is necessary. The aim of the present study was to evaluate the antimicrobial susceptibility of thermophilic Campylobacter strains isolated from patients with diarrhea, as well as from patients with diarrhea followed by postinfecti...

in this study, it was aimed to determine the effects of ship dismantling zones on distribution ofheavy metal resistance and level of antibiotic resistance of bacterial isolates from eastern aegean sea coast.thirteen isolates were identified by phylogenetic analysis using 16s rdna sequences which indicated that theisolates belonged to genus bacillus. these strains were investigated in respect of...

in this study, it was aimed to determine the effects of ship dismantling zones on distribution ofheavy metal resistance and level of antibiotic resistance of bacterial isolates from eastern aegean sea coast.thirteen isolates were identified by phylogenetic analysis using 16s rdna sequences which indicated that theisolates belonged to genus bacillus. these strains were investigated in respect of...

We have compared the rates of infection and resistance in an animal model of an orthopaedic procedure which was contaminated with a low-dose inoculum of Staphylococcus epidermidis. We randomised 44 Sprague-Dawley rats to have bone cement implanted subcutaneously containing either gentamicin or saline (control). The wound was inoculated with a dilute solution of gentamicin-sensitive Staphylococc...

Viridans streptococci are thought to be highly susceptible to penicillin and streptomycin. We recently encountered a unique group of 15 isolates from South Africa epidemiologically related to the isolation of penicillin-resistant pneumococci. These organisms were highly resistant to penicillin (PCN) (minimal inhibitory concentration, 1 to 32 micrograms/ml) and streptomycin (SM) (minimal inhibit...

BACKGROUND Anti-microbial lock solutions (AML), in conjunction with systemic antibiotics, may successfully treat tunnelled haemodialysis catheter-related bloodstream infections (CR-BSI). It is unknown whether AML promote anti-microbial resistance. METHODS This is a retrospective cohort study of all CR-BSI (2003-2006) in our dialysis unit. Controls (n = 265) were treated with systemic vancomyc...

The in vivo activities of cefsulodin, sulbenicillin, and gentamicin were compared in mice infected intraperitoneally with Pseudomonas aeruginosa. In mice infected with sulbenicillin- and gentamicin-susceptible strains, cefsulodin was about 12 to 60 times more active than sulbenicillin and had an activity similar to gentamicin. In mice, the activity of cefsulodin was independent whether the stra...

Pseudomonas aeruginosa is one of the most virulent and frequently encountered infectious agents affecting the cornea (Allen and Mangiaracine, 1964). Unhappily, its destructive effect on ocular tissues cannot always be prevented by the antibiotics currently available. The best anti-Pseudmonas drugs are colistin, polymyxin B, and gentamicin (Burns, 1969; Gordon, 1970), but Pseudomonas strain-resi...