the previous studies show that a high percentage of traffic accidents take place in two-lane rural highways and most of which happen at horizontal curves. meanwhile the horizontal alignment is often subject to hard topographic conditions where because of economic aspects designers are forced to design horizontal curves at grades. vertical angle of longitudinal slope reduces the normal force of ...

Characterized by simultaneous measurement of the effects of experimental factors and their interactions, the economic and efficient factorial design is well accepted in microarray studies. To date, the only statistical method for analyzing microarray data obtained using factorial design has been the analysis of variance (ANOVA) model which is a gene by gene approach and relies on multiple assum...

physiological effect of five levels of water stress (0,-0.3,-6,-9 and -1.2mp) was studied on seed germination and tigella as well as radicule growth length in two different artemisia species namely: artemisia spicigera and artemisia fragrans. polyethylene glycol (peg) was used to provide appropriate water potentials. a total of 50 seeds were sown from each artemisia species. experimental design...

This article first presents three-level simplex designs of k+1 runs for k factors. Each simplex design is composed of k treatment combinations from a two-level factorial design, plus an additional base run that represents a third level for each factor. These orthogonal, first-order designs are simple to construct. Furthermore, simplex designs can be augmented to construct second-order simplex s...

PURPOSE The objective of this work was to develop a bioadhesive topical gel of sertaconazole nitrate with the help of response-surface approach. METHODS Experiments were performed according to a 3-level factorial design to evaluate the effects of two independent variables [amount of Carbapol 934 = X1) and Sodium carboxymethylcellulose (NaCMC) = X2)] on the bioadhesive character of gel, rheolo...