نتایج جستجو برای: leukocyte

تعداد نتایج: 33409  

2012
Carola T. Murphy Kenneth Nally Fergus Shanahan Silvia Melgar

Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is associated with enhanced leukocyte infiltration to the gut, which is directly linked to the clinical aspects of these disorders. Thus, leukocyte trafficking is a major target for IBD therapy. Past and emerging techniques to study leukocyte trafficking both in vitro and in vivo have expanded our knowledge o...

2006
MICHAEL STEFANIDAKIS Erkki Koivunen Carl G. Gahmberg Jari Ylänne Jukka Westermarck Antti Vaheri

REVIEW OF THE LITERATURE LEUKOCYTE ADHESION AND MIGRATION THE LEUKOCYTE MIGRATION CASCADE NEUTROPHIL FUNCTION AND ADHESION DURING INFLAMMATION Granulopoiesis and subsets of neutrophil granules INTEGRINS AND THEIR LIGANDS Structure and function of leukocyte β2 integrins Activation of leukocyte β2 integrins MATRIX METALLOPROTEINASES CLASSIFICATION OF MMPs STRUCTURAL FEATURES OF MMPs REGULATION OF...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2001

Journal: :European Journal of Immunology 2012

Journal: :Journal of Experimental Medicine 1973

آقایی‌پور, مهناز, سلیمانی فریزهندی, علی, پورفتح‌اله, علی‌اکبر ,

 Preparation conditions and platelet storage for transfusion may cause platelet activation, which contributes to decreased ability of stored platelet to function and survive in vivo after transfusion compared with that seen with freshly prepared platelets. Using flowcytometry, we investigated platelet membrane expression of CD62P, CD63 in platelet stored for up to 3 days under standard blood ba...

Mehrnoosh Sabzeghabaie , Nasim Seyfi, Sara Dehghankhalili,

Objective: Leukocyte adhesion deficiency(LAD) is a scarce, autosomal recessive inherited disorder . LAD-I which is the most common type occurs due to mutations on the CD18 gene. This mutation leads to absence or severe reduction of leukocyte cell surface expression of ß2 integrin molecules which are necessary for the adhesion of the leukocytes to the endothelial cells, transendothelial mi...

Journal: :The Journal of clinical investigation 2007
Raogo Ouedraogo Yulan Gong Brett Berzins Xiandong Wu Kalyankar Mahadev Kelly Hough Lawrence Chan Barry J Goldstein Rosario Scalia

This study reports on what we believe are novel mechanism(s) of the vascular protective action of adiponectin. We used intravital microscopy to measure leukocyte-endothelium interactions in adiponectin-deficient (Ad(-/-)) mice and found that adiponectin deficiency was associated with a 2-fold increase in leukocyte rolling and a 5-fold increase in leukocyte adhesion in the microcirculation. Meas...

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