Leucocyte Alkaline Phosphatase Activity (LAPA) in normal healthy individuals was lound to be in the range 17-110. It was markedly increased in patients with myeloid leukemoid reaction (MLR) in the range 100-220. However it was decreased in patients with chronic myeloid leukaemia (CML) in the range 0-16. Increased LAPA in MLR is indicative of enhanced digestive capability of neutrophils while de...

A concise synthesis of rubioncolin B is described, which features an unprecedented intramolecular Diels-Alder reaction involving an ortho-quinone methide and a naphthofuran moiety. The ortho-quinone methide is generated through a surprisingly facile tautomerization of a para-quinone.

A near-infrared chemosensor for palladium based on the Tsuji-Trost reaction was developed. It displayed specific and ratiometric fluorescent responses toward palladium with a distinct color change from green to blue in aqueous media. PEG400 was employed as the reducing agent and palladium ligand instead of water-insoluble triphenylphosphine. The chemosensor's bioimaging potential was demonstrat...