Discourse comprehension is a hallmark of human social behaviour and refers to the act of interpreting a written or spoken message by constructing mental representations that integrate incoming language with prior knowledge and experience. Here, we report a human lesion study (n = 145) that investigates the neural mechanisms underlying discourse comprehension (measured by the Discourse Comprehen...

Great effort has been put into the development of diagnosis methods for the most dangerous type of skin diseases Melanoma. This paper aims to develop a prototype capable of segment and classify skin lesions in dermoscopy images based on ABCD rule. The proposed work is divided into four distinct stages: 1) Pre-processing, consists of filtering and contrast enhancing techniques. 2) Segmentation, ...

BACKGROUND Ablation lesion depth caused by radiofrequency-based renal denervation (RDN) was limited to <4 mm in previous animal studies, suggesting that radiofrequency-RDN cannot ablate a substantial percentage of renal sympathetic nerves. We aimed to define the true lesion depth achieved with radiofrequency-RDN using a fine sectioning method and to investigate biophysical parameters that could...

© 2015 Egyp an Journal of Neurosurgery. All rights reserved Background. Lesion therapy has been used for Parkinson’s disease (PD) and other movement disorders since the early 1900s. More recently, be er understanding of the pathophysiological basis underlying the development of PD in addition to the advances in imaging technology and electrophysiological techniques used for localization of brai...

In this paper we present an accelerated system for diagnosing skin lesions based on digitized dermatoscopic color images. This system is composed mainly of three levels : lesion detection, lesion description features selection and decision. The lesion detection level consists in the preprocessing of the lesion image in order to remove the undesired objects from the original image. Then, the ext...

OBJECTIVE To investigate whether patterns of swallowing difficulties were associated with the location of the brain lesion, cognitive function, and severity of stroke in stroke patients. METHOD Seventy-six patients with first-time acute stroke were included in the present investigation. Swallowing-related parameters, which were assessed videofluoroscopically, included impairment of lip closur...

BACKGROUND Stereotactic thermocoagulative lesions of the subthalamic nucleus (STN) have been shown to induce significant motor improvement in patients with Parkinson's disease (PD). PATIENTS AND METHODS 89 patients with PD were treated with unilateral subthalamotomy. 68 patients were available for evaluations after 12 months, 36 at 24 months and 25 at 36 months. RESULTS The Unified Parkinso...

Objectives- To evaluate the most important bovine digital lesions in shahrekord area and its correlation with locomotion scoring. Study Design- Cross- Sectional descriptive study. Animals- five hundred and eighteen cows inspected in two seasons. Methods- Three dairy farms on three scales (1: Large, approximately 900 milking cows, 2: Medium, approximately 100 milking cows, and 3: Small, app...

The optimum management for recurrent glenohumeral instability with significant humeral head defects remains controversial. The purpose of this study was to compare outcomes and recurrence rates between patients who underwent osteochondral substitute grafting and patients who underwent remplissage to treat recurrent shoulder instability from an engaging Hill-Sachs defect with a Bankart lesion. T...

AIM This study aimed to systematically map the severity of mirror movements in both hands in a prospective cohort of children with unilateral cerebral palsy, and to explore the relationship with hand function and brain lesion type. METHOD Seventy-eight children were included (41 males, 37 females; age 9y 4mo, SD 3y 1mo, range 5-15y). Mirror movements were scored during three repetitive tasks ...