نتایج جستجو برای: leptin transcript
تعداد نتایج: 49208 فیلتر نتایج به سال:
Introduction: Leptin, the obese (ob) gene product, is a cytokine-like hormone secreted mainly from adipose tissue acting on a receptor site in the hypothalamus to inhibit food intake and stimulate energy expenditure. A G-2548G polymorphism in the leptin gene promoter has a strong influence on leptin gene expression and adipose tissue secretion. The aim of this study was to examine the associati...
Objective(s): Leptin is a hormone secreted by adipose tissue and is involved not only in the regulation of feeding and energy expenditure, but also its role in memory enhancement has been demonstrated as well. The partial transfer of leptin across the blood-brain barrier in obese individuals causes leptin resistance and prevents leptin reaching brain. On the other hand, studies have show...
Background: Adiponectin and leptin are hormones which are related to body fat tissues and body weight. In pregnant women, conflicting associations have been reported between the role of serum concentrations of adiponectin and leptin with infant birth weight. The aim of this study was to determine the association between maternal and cord blood adiponectin and leptin concentrations with birth w...
background: leptin and adiponectin are the two key metabolic hormones secreted from adipocytes to control food intake and energy expenditure. the action of both hormones in regulation of gonadotropin releasing hormone (gnrh) secretion from the hypothalamus is mediated through kisspeptins. kisspeptins are products of kiss-1 gene. leptin and adiponectin are modulators of kiss-1 expression in the ...
background: leptin is a polypeptide hormone secreted by white adipose tissue in proportion to body energy. although the participation of leptin in female reproduction is well established any role in male reproductive function is at best tenuous. objective: the objective of this study was to compare the leptin concentration in human seminal plasma and then the relationships between seminal lepti...
تغییرات غلظت پلاسمایی هورمونهای تیروئیدی در گوسفندان تحت محدودیت انرژی و اثر تزریق وریدی لپتین بر آن
the aim of this study was to determine changes in the concentration of leptin and thyroid hormone in energyrestricted ewes and effect of leptin injection on thyroid hormone level. in the first experiment, 28 ewes were assigned to two groups(n=14). ewes were fed by a ration that provided 60% or 100% of maintenance energy requirements during 71 days. blood samples were collected and body w...
To determine possible genetic influences on the steady-state concentrations of several key transcription factor transcripts and the transcript concentrations for adipocyte-characteristic proteins, young, genetically obese and lean pigs were given ad libitum access or feed or were restrictively fed at 50% of ad libitum intake for 5 wk. Obese pigs were smaller and fatter than lean pigs, whether i...
Although the discovery of leptin (1) has failed, so far, to fulfill its promise as the magic bullet for the treatment of obesity, it has focused attention on the blood-brain barrier (BBB) and the role of endogenous peptides/polypeptides in food ingestion. The article by Fliedner, Schulz, and Lehnert (2) in this issue of Endocrinology does more than add to the 20,000 papers on the BBB, 10,000 on...
background obesity is a medical problem in survivors of childhood acute lymphoblastic leukemia. obesity is associated with many complications, so it is important to investigate the respective etiology. leptin is a protein synthesized in the fatty tissue and is effective in the control of obesity. survey of leptin in acute lymphoblastic leukemia (all) survivors could be helpful in controlling ob...
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