A 39-years-old male patient with previously treated borderline lepromatous (BL) leprosy, presented paresthesia and dysesthesia in the feet hands, associated fever, arthralgia, erythema nodosum during a Type-2 leprosy reaction (LR) episode. This evolved 3 days to flaccid tetraparesis areflexia, gait impairment, addition clinical signs of dysautonomia, such as tachycardia, tachydyspnea, cranial n...

A 25-year-old male patient with florid lepromatous leprosy presented with right axillary lymphadenopathy and a discharging sinus. He also had scabies with chronic right otitis media. Histopathological examination of the lymph node revealed lepromatous lymphadenitis coexisting with tuberculosis. This unusual combination of two different clinical entities is recorded in this case report.

We investigated the impact of multidrug therapy (MDT) on the epidemiological pattern of leprosy in Juiz de Fora, Brazil, from 1978 to 1995. Evaluation of 1,283 medical charts was performed according to the treatment regimen used in two different periods. Following the introduction of MDT in 1987, prevalence of leprosy decreased from 22 patients/10,000 inhabitants to 5.2 patients/10,000 inhabita...

population injected drugs in the six months before arrest.45 If we assume from our data that 8% of them were HIV positive that gives an estimated total of 203 HIV positive male drug injectors in the sentenced population. The corresponding figures for women (about 168 recent injectors, and 15% HIV positive) suggest a total of 25 HIV positive women in prison. At any time, therefore, the total num...

OBJECTIVES Leprosy remains a public health concern in Malaysia and globally. We aim to review the characteristics of leprosy patients in a tertiary institution in urban Malaysia. DESIGN This is a case series of 27 leprosy patients who presented between 2008 and 2013. RESULTS The majority of our patients consisted of male (74.1%), Malaysian (63.0%), blue collar workers (51.9%) and married (5...

Attention is drawn to a Type 1 reaction masquerading clinically as ENL. Histology showed no evidence of ENL but suggested heightened T-cell activity (CMI), a characteristic feature of Type 1 reaction. We present a case of a 29 year old man diagnosed as lepromatous leprosy with recurrent Type 2 reaction treated with thalidomide for 2 years. The patient was referred to our institute from a teachi...

leprosy is a rare but important infectious disease caused by mycobacterium leprae . word health organization suggested a strategy to reduce the prevalence of the disease to less than one per 10000 people. it seems that the leprosy is now in its elimination stage because during a period of ten years only few new cases were found in iran. we studied 157 new leprosy cases that were referred to and...

A 35-year-old male with lepromatous leprosy showed significant progression of the disease on initial examination. Along with typical lepromatous skin lesions, many scar-forming lesions were present, mainly on his extremities. Some lesions showed erosive surfaces. From clinicopathological findings, these lesions were suspected to be due to the partial excretion of intradermal lepromatous granulo...

We report a case of multiple relapses in a lepromatous leprosy patient after treatment with World Health Organisation (WHO) recommended multibacillary multidrug therapy (MBMDT). The patient responded well to reintroduction of MDT after each relapse.

Wild nine-banded armadillos (Dasypus novemcinctus) in the south central United States are highly endemic natural hosts of Mycobacterium leprae. Surveys conducted over the last 30 years on more than 5000 animals confirm that the infection is present among armadillos in Arkansas, Louisiana, Mississippi and Texas. Highest prevalence rates are found among the animals in low-lying alluvial and coast...