نتایج جستجو برای: leishmania tarentolae
تعداد نتایج: 13657 فیلتر نتایج به سال:
Carbaporphyrin ketals are porphyrinoid compounds in which a pyrrole ring of a typical porphyrin macrocycle has been replaced by a ketal-substituted indene ring. It was recently demonstrated that these compounds are effective in vitro against Leishmania tarentolae. Their in vitro effectiveness is increased when they are exposed to visible light; they act as photosensitizers capable of mediating ...
Low protein solubility and inclusion body formation represent big challenges in production of recombinant proteins in Escherichia coli. We have recently reported functional expression of hydroxynitrile lyase from Manihot esculenta, MeHNL, in E. coli with high in vivo solubility and activity using directed evolution. As a part of attempts to clarify the mechanism of this phenomenon, we have desc...
All mitochondrial tRNAs in kinetoplastid protozoa are encoded in nuclear DNA and transported into the mitochondrion (Simpson et al., Nucl Acids Res 1989;17:5427-5445; Hancock and Hajduk, J Biol Chem 1990;265:19208-19215). It has been proposed that tRNAs in these cells are imported into the mitochondrion as 5'-extended precursors which are processed by a mitochondrial RNase P-like activity (Hanc...
All mitochondrial tRNAs of the kinetoplastid protozoan Leishmania tarentolae are encoded in the nucleus and are imported from the cytosol into the mitochondrion. We previously reported the partitioning of five tRNAs and found that all were shared between the two compartments to different extents. To increase our knowledge of the tRNAs of this organism, and to attempt to understand the signals i...
An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae.
زمینه و هدف : پروتئین اریتروپویتین انسانی هورمونی گلیکوزیله با وزن مولکولی 40 کیلو دالتون است که در کلیه سنتز شده و در تکثیر و تمایز اریتروسیت ها نقش دارد. این پروتئین دارویی با نام تجاری «اپویتین» شناخته شده و کاربرد موثری در درمان آنمی، سرطان و عفونت های ناشی از hiv ایفاء می کند. این مطالعه به منظور ارزیابی استفاده از میزبان انگلی لیشمانیا تارانتولا (leishmania tarentolae) به منظور تولید فرم ...
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