نتایج جستجو برای: ldha

تعداد نتایج: 345  

Journal: :The Journal of pathology 2015
Angela Kwok-Fung Lo Christopher W Dawson Lawrence S Young Chuen-Wai Ko Pok-Man Hau Kwok-Wai Lo

Non-keratinizing nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) infection. The EBV-encoded latent membrane protein 1 (LMP1) is believed to play an important role in NPC pathogenesis by virtue of its ability to activate multiple cell signalling pathways which collectively promote cell proliferation, transformation, angiogenesis, and invasiveness, as well as mo...

Journal: :Physiological genomics 2011
Rajaa Hussien George A Brooks

We hypothesized that dysregulation of lactate/pyruvate (monocarboxylate) transporters (MCT) and lactate dehydrogenase (LDH) isoforms contribute to the Warburg effect in cancer. Therefore, we assayed for the expression levels and the localizations of MCT (1, 2, and 4), and LDH (A and B) isoforms in breast cancer cell lines MCF-7 and MDA-MB-231 and compared results with those from a control, untr...

Journal: :Annals of the Rheumatic Diseases 2021

Background: Interferon-gamma (IFNg) producing effector T cells play the leading role in triggering and perpetuation of inflammation rheumatoid arthritis. Inflammation leads to metabolic reprogramming high energy consumption supporting proliferation IFNg production. Being a part chromosomal passenger complex, oncoprotein survivin is essential for cell proliferation. It has also been identified a...

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