In 1996, Phil Bryden, Mike Corballis, and Chris McManus released the first issue of Laterality. These founding editors pointed out in their editorial how surprisingly long it took to have a journal...

Laterality refers to the contention that the left and right hemisphere of the brain process information differently. Currently under debate is whether there is laterality of phonological and orthographic processing. Two experiments used a lexical decision task and a priming procedure along with a distractor to the left or right visual field to test laterality. Experiment I manipulated sound sim...

Organ formation requires the precise assembly of progenitor cells into a functional multicellular structure. Mechanical forces probably participate in this process but how they influence organ morphogenesis is still unclear. Here, we show that Wnt11- and Prickle1a-mediated planar cell polarity (PCP) signalling coordinates the formation of the zebrafish ciliated laterality organ (Kupffer's vesic...

The vertebrate brain develops from a bilaterally symmetric neural tube but later displays profound anatomical and functional asymmetries. Despite considerable progress in deciphering mechanisms of visceral organ laterality, the genetic pathways regulating brain asymmetries are unknown. In zebrafish, genes implicated in laterality of the viscera (cyclops/nodal, antivin/lefty and pitx2) are coexp...

BackgroundCarotid stenosis can profoundly affect cerebral hemodynamics, which cannot simply be inferred from the degree of stenosis. We quantified and mapped distribution blood flow rate (BFR) in arteries before after carotid endarterectomy using four-dimensional (4D) phase-contrast (PC) magnetic resonance imaging (MRI).MethodsNineteen patients (age, 71 ± 6 years; 2 women) with symptomatic (?50...

Lateralisation of responses to presentation of a simulated predator was investigated in three species of toads: two European species (the common toad, Bufo bufo, and the green toad, Bufo viridis) and one species introduced to Australia from South America, the cane toad Bufo marinus . First a simulated snake was presented moving rapidly towards the toad in the frontal field of vision and the toa...

There are formidable problems in studying how 'real' music engages the brain over wide ranges of temporal scales extending from milliseconds to a lifetime. In this work, we recorded the magnetoencephalographic signal while subjects listened to music as it unfolded over long periods of time (seconds), and we developed and applied methods to correlate the time course of the regional brain activat...

THREE TERMS DEFINE BRAIN BEHAVIORAL LATERALITY hemispheric dominance identifies the cerebral hemisphere producing one's first language. Hemispheric asymmetry locates the brain side of non-language skills. A third term is needed to describe a person's binary thinking, learning, and behaving styles. Since the 1950s split-brain studies, evidence has accumulated that individuals with right or left ...

PURPOSE To examine distributed patterns of language processing in healthy controls and patients with epilepsy using magnetoencephalography (MEG), and to evaluate the concordance between laterality of distributed MEG sources and language laterality as determined by the intracarotid amobarbital procedure (IAP). METHODS MEG was performed in 10 healthy controls using an anatomically constrained, ...

In mouse, the establishment of left-right (LR) asymmetry requires intracellular calcium (Ca(i)(2+)) enrichment on the left of the node. The use of Ca(i)(2+) asymmetry by other vertebrates, and its origins and relationship to other laterality effectors are largely unknown. Additionally, the architecture of Hensen's node raises doubts as to whether Ca(i)(2+) asymmetry is a broadly conserved mecha...