OBJECTIVES Implantation of left ventricular assist devices (LVADs) early after acute myocardial infarction (MI) has traditionally been thought to be associated with high mortality rates due to technical limitations and severe end-organ dysfunction. At some experienced centers, doctors have refrained from earlier operation after MI to allow for a period of hemodynamic and end-organ stabilization...

I am concerned about the implications of the Editorial by Drs. Lown and Axelrod which appeared in the October 1972 issue of Circulation. Although the authors rightfully point out the numerous technical problems still to be overcome in the development of such defibrillators, their conclusions in the last three paragraphs indicate a heavy bias in favor of "practical research." Although Dr. Lown h...

Three patients with complete heart block had a high resistance to electrical stimulation of the endocardium through transvenous pacemaker systems. One patient died; one needed reoperation for implantation of epicardial electrodes; and the third required a generator of higher current. The present enthusiasm for permanent transvenous implantation of pacemakers must be tempered somewhat by the kno...

I am concerned about the implications of the Editorial by Drs. Lown and Axelrod which appeared in the October 1972 issue of Circulation. Although the authors rightfully point out the numerous technical problems still to be overcome in the development of such defibrillators, their conclusions in the last three paragraphs indicate a heavy bias in favor of "practical research." Although Dr. Lown h...

Muller, and P. R. Renne, Department of Physics, University of California, Berkeley, California 94720, USA, Presently at Chicago Center for Cosmochemistry and Department of Geophysical Sciences, University of Chicago, Chicago, Illinois 60637, USA ([email protected]), Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA, Berkeley Geochronology Center, 2755 Ridge Road, ...

embolectomy has long been the gold standard for treating limbs acutely threatened by arterial occlusion. delayed embolectomy has not been investigated adequately due to the belief that accompanying mortality and morbidity render the case futile. following our previous experience with late arterial repair for leg or knee salvage i we applied the same principle to limbs threatened with prolonged ...

''/Oh n * * a"Cll| LiApCClUUUCd 111 r^uiuuici j u /lf/tum i . uuiujftt/t ^?? U5U ress, 1963, 305.) Cla'nftSyCll0therapists ^ave ̂ een susPici?us ?f the credentials of many investigators who 3ppro ?^udy their results. Only too often has investigation been based upon a mechanistic 4s ^ s. ln which the concepts were of illnesses as discrete entities, and of psychotherapy Patien^ndard commodity, to ...