Introduction: Low-energy helium-neon (He-Ne) laser beam lightis used in combination with sodium hypochlorite (Na2HOCl3) for clinical purposes. Regarding this, the present study aimed to investigate the effect of He-Ne laser (632.8 nm) and sodium hypochlorite on the calf thymus double-stranded deoxyribonucleic acid (ctdsDNA) molecule.  Materials and Methods: For the purpose of the study, ctdsDNA...

SUMMARY We have discussed in this article, about usages of Laser (Cortype) In Neurological - Surgery, In the beginning of the article, historical considerations have been written, then specifications of laser light have been noted, including the functions of laser. In this article, types of laser have been matched. In the another part of article, advantages of Co2 . laser have been mentioned,...

Background and Aim: Diode laser is a great choice for soft tissue surgery. The diode laser is partially absorbed by hard dental tissues, making it safe for soft tissue surgery. This study aimed to compare the tissue thermal changes induced by three types of diode lasers at 810, 940, and 980nm wavelengths. Materials and Methods: In this in-vitro experimental study, using a diode laser device (c...

Background and Aim: Bleaching can improve the color of restorative materials and resolve problems related to discoloration or color mismatch. This study evaluated the effect of in-office bleaching method in conjunction with two different laser wavelengths on color change of two types of glass-ionomer restorative materials (light-cure and self-cure). Materials and Methods: In this experimenta...

The aim of this study was to enhance the effectiveness of photo thermal therapy (PTT) in the targeting of superficial bladder cancers using a green light laser in conjunction with gold nanoparticles (GNPs) conjugated to antibody fragments (anti-EGFR). GNPs conjugated with anti-EGFR-antibody fragments were used as probes in the targeting of tumor cells and then exposed to a green laser (532nm), ...

Nowadays, Erbium: YAG laser resurfacing of periorbital skin has become a very popular method of wrinkle reduction. Seven patients with Fitzpatrick skin phototypes of II to V were treated with a 2940 nm Erbium: YAG laser system for resurfacing of periorbital wrinkles. Photographic evalution performed before and after treatment. Patients were visited at 1,2,3,5,7,14,30 and 60 days after laser res...

Specialized gold nanostructures are of interest for the development of alternative treatment methods in medicine. Photothermal therapy combined with gene therapy that supports hyperthermia is proposed as a novel multimodal treatment method for prostate cancer. In this work, photothermal therapy using small (<100 nm) gold nanoparticles and near-infrared (NIR) laser irradiation combined with gene...

Selective targeting of diseased cells can increase therapeutic efficacy and limit off-target adverse effects. We developed a new tool to selectively perforate living cells with functionalized gold nanoparticles (AuNPs) and near-infrared (NIR) femtosecond (fs) laser. The receptor CD44 strongly expressed by cancer stem cells was used as a model for selective targeting. Citrate-capped AuNPs (100 n...

The formation of glial scars after spinal cord injury (SCI) is one of the factors inhibiting axonal regeneration. Glial scars are mainly composed of reactive astrocytes overexpressing intermediate filament (IF) proteins such as glial fibrillary acidic protein (GFAP) and vimentin. In the current study, we delivered small interfering RNAs (siRNAs) targeting these IF proteins to SCI model rats usi...

A noninvasive and selective therapy, photodynamic therapy (PDT) is widely researched in clinical fields; however, the lower efficiency of PDT can induce unexpected side effects. Mitochondria are extensively researched as target sites to maximize PDT effects because they play crucial roles in metabolism and can be used as cancer markers due to their high transmembrane potential. Here, a mitochon...