The aim of the present study was to detect the elastic modulus (stiffness) of the livers of rabbits with non-alcoholic and alcoholic fatty liver disease using real-time shear wave elastography (SWE), and to investigate the fibrosis development process in the formation of fatty liver. The stiffness of the fatty livers in rabbit models prepared via feeding with alcohol or a high-fat diet were mea...

Non-alcoholic fatty liver disease (NAFLD) is a serious clinicopathological condition that recognized as the most frequent chronic disease, affecting 14–30% of world’s population. The prevalence NAFLD has rapidly grown and correlated with growth in obesity type 2 diabetes, among other factors. often results long-term complications including cardiovascular cirrhosis, fibrosis. This paper provides...

The prevalence of obesity increases worldwide in the last several decades affecting up to 30% of adults in some of the EU countries [1]. Obesity is a major risk factor for type 2 diabetes, non-alcoholic fatty liver disease, dyslipidemia, hypertension, cardiovascular disease, sleep apnea, and gall bladder disease [2]. Recent reports alarm that even metabolically healthy obese persons are in risk...

The prevalence of obesity increases worldwide in the last several decades affecting up to 30% of adults in some of the EU countries [1]. Obesity is a major risk factor for type 2 diabetes, non-alcoholic fatty liver disease, dyslipidemia, hypertension, cardiovascular disease, sleep apnea, and gall bladder disease [2]. Recent reports alarm that even metabolically healthy obese persons are in risk...

Non-alcoholic fatty liver disease (NAFLD) has become one of the top concerns for the practicing hepatogastroenterologist due to the obesity epidemic and it’s potential to progress to advanced liver disease which significantly impacts on overall and liver-related mortality. NAFLD may cause the liver to swell (steatohepatitis). An inflammation in liver may cause scarring (cirrhosis) over time and...

Non-alcoholic fatty liver disease (NAFLD) covers a spectrum of disorders ranging from simple steatosis (non-alcoholic fatty liver, NAFL) to non-alcoholic steatohepatitis (NASH) and cirrhosis. NAFL increases the risk of liver fibrosis. If the liver is fatty due to causes of insulin resistance such as obesity and physical inactivity, it overproduces glucose and triglycerides leading to hyperinsul...

Prevalence of non-alcoholic steatohepatitis (NASH) rises steadily in Western countries with the obesity epidemic. NASH is associated with activation of liver fibrogenesis and predisposes to cirrhosis and associated morbi-mortality. The cannabinoid system is increasingly emerging as a crucial mediator of acute and chronic liver injury. Recent experimental and clinical data indicate that peripher...

BACKGROUND It is uncertain whether non-alcoholic fatty liver disease (NAFLD) or abdominal obesity is more associated with atherosclerosis. The aim of this study was to determine whether NAFLD or abdominal obesity is more strongly associated with subclinical atherosclerosis represented by coronary artery calcification (CAC). METHODS A total of 21,335 male participants in a health screening pro...