The decision to treat elevated arterial pressure in pregnancy depends on the risk and benefits imposed on the mother and the fetus. Treatment for mild-to-moderate hypertension during pregnancy may not reduce maternal or fetal risk. Severe hypertension, on the other hand, should be treated to decrease maternal risk. Methyldopa and beta-adrenoceptor antagonists have been used most extensively. In...

Vasodilators are important adjuncts to anesthetic management in a variety of clinically encountered situations. Examples include: congestive heart failure, preeclampsia/eclampsia, management of aortic cross-clamping and treatment of perioperative hypertension. In this article, the authors review four commonly utilized vasodilating agents: sodium nitroprusside, labetalol, hydralazine and nitrogl...

The hyperadrenergic syndrome that occurs in tetanus is characterised by hypertension, tachycardia, and increased systemic arteriolar resistance. A 74 year old man with tetanus was found to have very high catecholamine concentrations--as high as those in phaeochromocytoma--and the fluctuations in blood pressure and heart rate were measured to see whether they paralleled changes in the catecholam...

Acute-onset, severe systolic hypertension; severe diastolic hypertension; or both can occur during the prenatal, intrapartum, or postpartum periods. Pregnant women or women in the postpartum period with acute-onset, severe systolic hypertension; severe diastolic hypertension; or both require urgent antihypertensive therapy. Introducing standardized, evidence-based clinical guidelines for the ma...

Hypertensive disorders of pregnancy (HDP) are rising in prevalence and associated with adverse maternal infant health outcomes. Current guidelines recommend labetalol, nifedipine, methyldopa as acceptable first-line agents to treat HDP outpatient settings. However, the current practice regarding antihypertensive medication usage selection remain unclear. A retrospective, observational cohort st...