BACKGROUND KPC-type carbapenemases are increasingly prevalent in parts of the USA and Israel and are an emerging concern in South America, Europe and China. We investigated the UK's first two KPC-producing Klebsiella pneumoniae isolates. METHODS The isolates were referred to the UK's national reference laboratory for confirmation of carbapenem resistance. Susceptibilities were determined by a...

Increased incidence of infections due to Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae (KPC-Kp) was noted among patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) at a single hospital. An epidemiologic investigation identified KPC-Kp and non-KPC-producing, extended-spectrum β-lactamase (ESBL)-producing Kp in cultures from 2 endoscopes. Genotypi...

We used the HI data from the LAB survey to map the ring-shaped gap in HI density which lies slightly outside the solar circle. Adopting R0= 7.5 kpc, we find and average radius of 8.3 kpc and an average gap width of 0.8 kpc. The characteristics of the HI gap correspond closely to the expected ones, as predicted by theory and by numerical simulations of the gas flow near the corotation resonance.

1. Yigit H, Queenan AM, Anderson GJ et al. Novel carbapenemhydrolyzing b-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother 2001; 45: 1151–61. 2. Smith Moland E, Hanson ND, Herrera VL et al. Plasmidmediated, carbapenem-hydrolysing b-lactamase, KPC-2, in Klebsiella pneumoniae isolates. J Antimicrob Chemother 2003; 51: 711–4. 3. Yigit H, Que...

The radio-quiet quasar SDSS J1536+0441 shows two broad-line emission systems that Boroson & Lauer interpret as a candidate binary black-hole system with a separation of 0.1 pc (0.02 mas). From new VLA imaging at 8.5 GHz, two faint sources, separated by 0.97 (5.1 kpc), have been discovered within the quasar’s optical localization region. Each radio source is unresolved, with a diameter of less t...

OBJECTIVES To investigate the first KPC carbapenemase-producing Klebsiella pneumoniae isolate from a Greek hospital, including phenotypic methods to aid recognition of this resistance type. METHODS A carbapenem-resistant clinical isolate of K. pneumoniae was recovered from a hospitalized Greek patient. Detailed susceptibility testing was carried out by the agar dilution method. The isolate wa...

OBJECTIVES Production of carbapenemase, especially Klebsiella pneumoniae carbapenemases (KPC), is one of the antibiotic resistance mechanisms of Enterobacteriaceae such as Klebsiella oxytoca. This study aimed to investigate and identify KPC-producing K. oxytoca isolates using molecular and phenotypic methods. METHODS A total of 75 isolates of K. oxytoca were isolated from various clinical sam...

The creation and the use of knowledge have increasingly been regarded as important issues for management. A wide range of studies have investigated this topic during the past decade. Notwithstanding these contributions, very little systematic attention has been paid to the linkages between knowledge capabilities and strategy implementation. Drawing from knowledge capabilities theory and strateg...

BACKGROUND Klebsiella pneumoniae carbapenemase (KPC) is one of the carbapenemases that can cause multi-antibiotics resistance in Acinetobacter baumannii. A simple phenotypic rapid and accurate test for the detection of A. baumannii - KPC-producer can be useful in treating related infections. The aim of this study was to determine the synergism effect of boronic acid (BA), as an inhibitor, and m...

The formation of globular clusters is still an unsolved problem. Though most scenarios assume a massive molecular cloud as the progenitor, it is unclear, how the cloud is transformed into a star cluster. Here a scheme of supernova (SN) induced cluster formation is investigated. In this scenario the expanding SN shell accumulates the mass of the cloud. This is accompanied by fragmentation result...