Kidney injury molecule-1 (Kim-1) is a type 1 membrane protein maximally upregulated in proliferating and dedifferentiated tubular cells after renal ischemia. Because epithelial dedifferentiation, proliferation, and local ischemia may play a role in the pathophysiology of autosomal dominant polycystic kidney disease, we investigated Kim-1 expression in a mouse model of this disease. In the Pkd2(...

BACKGROUND Kidney injury molecule-1 (KIM-1) is expressed in tubular epithelial cells after injury and may have a role in the development of renal graft fibrosis. In this study we evaluated the molecular and protein expressions of KIM-1 in dysfunctional allografts and also mRNA KIM-1 expression in urine as potential biomarkers of graft fibrosis. METHODS Protein and mRNA levels in renal tissue ...

Kidney injury molecule-1/T cell IgG and mucin containing 1 (KIM-1/TIM-1) is a type 1 membrane receptor [1] which we identified as the most upregulated proximal tubular cell (PTC) protein following a variety of kidney injuries in animal models and human diseases [1] (Figure 1A). While KIM-1 (also known as hepatitis A virus cellular receptor-1 (HAVCR-1)) quickly was recognized as a promising biom...

Kidney injury molecule-1 (KIM-1), a recently discovered transmembrane protein, is expressed in dedifferentiated proximal renal tubular epithelial cells in damaged regions. It may participate in the progress of renal injury or repair. Many studies have illustrated the different functions of KIM-1 in various renal diseases including protective functions in acute kidney injury and damaging functio...

The aim of the present study was to investigate whether urinary kidney injury molecule‑1 (KIM‑1) presents a suitable early diagnostic biomarker of obstructive nephropathy‑induced acute kidney injury (AKI), and to develop a rapid detection method for urinary KIM‑1. Obstructive AKI was induced in an experimental rat model by a unilateral ureteral obstruction (UUO) operation. Macro‑ and micromorph...

J. Choe, K. S. Kim, H. B. Kim, S. Park, J. Kim, S. Kim, B. Kim, S. H. Cho, J. Y. Cho, I. H. Park, J. H. Cho & M. Song 1 Department of Animal Science and Biotechnology, Chungnam National University, Daejeon 34134, South Korea 2 Chung Cheong Buk-do Institute of Livestock and Veterinary Research, Cheongju 363931, South Korea 3 Department of Animal Resource Science, Dankook University, Cheonan 3111...

Markov chain Hebbian learning algorithm with ternary synaptic units Guhyun Kim, Vladimir Kornijcuk, Dohun Kim, Inho Kim, Jaewook Kim, Hyo Cheon Woo, Ji Hun Kim, Cheol Seong Hwang*, and Doo Seok Jeong* Center for Electronic Materials, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, 02792 Seoul, Republic of Korea Department of Materials Science and Engineering and Inte...

In ICCSA 2005, Lee, Kim, Kim, & Oh proposed a new (two-party) ID-based key agreement protocol, which they claimed to provide known key security resilience, forward secrecy, key compromise resilience, unknown key share resilience, and key control, however, without providing any security proofs. In this work, we demonstrate that their claims of known key security resilience and key control are fl...