Thirty patients of affective disorder who were on lithium for a year and thirty patients on antidepressant were studied in detail for renal functions. Our observation is that lithium therapy does not lead to any deterioration in kidney functions. The results are discussed.

Rapid signalling responses stimulated by steroid hormones have been detected in various tissues including the nephron. The significance of these responses in modulating the physiological effects elicited by mineralocorticoids, glucocorticoids and the reproductive hormones in the kidney is now becoming more evident. This review outlines how rapid signalling responses stimulated by these hormones...

Regulation of blood pressure is one of the important functions of Angiotensin I converting enzyme (ACE, EC. 3.4.15.1). ACE is widely distributed and appears to have several important physiological functions including its major role in blood pressure regulation. In the treatment of congestive heart failure, coronary artery disease, diabetic nephropathy etc.ACE inhibitors are used. The current st...

Lithium is an established treatment for bipolar disorder and an augmenting agent for treatment-resistant depression. Despite awareness of renal adverse effects, including chronic kidney disease, for the past five decades, there has been a lack of research evidence. This has led to debates around the existence and magnitude of the risk. This article discusses the current evidence base regarding ...

Aim: As liver and kidney failure have a direct effect on mortality, morbidity, and intensive care unit (ICU) length of stay in sepsis patients, maintaining their functions or minimizing the degree of failure should be one of the most important goals of therapy. In this retrospective study we investigated the effects of recently introduced adjuvant therapies on hepatorenal functions in septic IC...

We have characterized multiple transcripts from the band 3 gene expressed in rat and mouse kidney. In each species, the major transcript lacks sequence from the first three exons of the band 3 gene. The murine transcript predicts a kidney band 3 polypeptide with a truncated amino terminus, lacking the first 79 amino acids of erythroid band 3. When expressed in Xenopus oocytes this truncated ban...

in this paper, we introduce and investigate a subclass of analytic and bi-univalent functions in the open unit disk. upper bounds for the second and third coefficients of functions in this subclass are founded. our results, which are presented in this paper, generalize and improve those in related works of several earlier authors.

Ubiquitin-40S ribosomal protein S27a (RPS27A), ubiquitin-like Fubi, and (S30FAU) are ubiquitin-related proteins that involved in the regulation of immune-related functions such as cell cycle, expression, apoptosis. This study aimed to confirm molecular characteristics, gene expression analysis, antibacterial activity RPS27A S30FAU identified from starry flounder (15 flounders 128.7 ± 18.2 g). A...

Introduction: Ghrelin is an endogenous peptide that has diverse functions in the body. One of the newly recognized roles of this peptide is its antiapoptotic effect. However, this function has not been investigated in normobaric hypoxia- induced apoptosis in body organs. This study will examine the effect of ghrelin treatment on Bax-Bcl-2 gene expression in the kidney of chronic hypoxic rats. ...

Renal cell carcinoma is one of the most common urological tumors. The role of programmed cell death 1 ligand 1 (PD-L1) in renal cell carcinomas in predicting outcome of the patients is yet unclear. We analyzed the clinical and RNA-seq data of 522 kidney clear cell cancer, 259 kidney papillary cell carcinoma and 66 kidney chromophobe patients from The Cancer Genome Atlas (TCGA) database. In kidn...