نتایج جستجو برای: kidney damage

تعداد نتایج: 435635  

Journal: :Natural Product Communications 2023

Mitochondrial dysfunction and oxidative stress play essential roles in the pathogenesis of diabetic nephropathy (DN). The respiratory oxygen consumption status kidney mitochondria are closely associated with development DN. In this study, raspberry ketone (RK), predominant bioactive component extracted from raspberry, was applied to treat established DN mice model. This study investigated wheth...

Journal: :Journal of Translational Internal Medicine 2020

Journal: :Journal of Animal Science 2019

Journal: :Journal of the American College of Cardiology 2021

Administration of iodinated contrast medium (CM) during invasive cardiovascular procedures may be associated with impairment kidney function. Urinary dickkopf-3 (DKK3), a stress-induced renal tubular epithelium–derived glycoprotein, has been identified as biomarker predicting both acute injury (AKI) and persistent dysfunction. DKK3/creatinine ratio (uDKK3/uCr), urine serum neutrophil gelatinase...

2017
Alessandro Mauriello Valentina Rovella Filippo Borri Lucia Anemona Elena Giannini Erica Giacobbi Andrea Saggini Giampiero Palmieri Alessandro Anselmo Pierluigi Bove Gerry Melino Guardini Valentina Manfredi Tesauro D’Urso Gabriele Nicola Di Daniele

Background. Normalization of arterial pressure occurs in just a few patients with hypertensive chronic kidney disease undergoing kidney transplantation. Hypertension in kidney transplant recipients may be related to multiple factors. We aimed to assess whether hypertension in kidney-transplanted patients may be linked to reinnervation of renal arteries of the transplanted kidney. Methods. We ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Olivier Boutaud Kevin P Moore Brandon J Reeder David Harry Alexander J Howie Shuhe Wang Clare K Carney Tina S Masterson Taneem Amin David W Wright Michael T Wilson John A Oates L Jackson Roberts

Hemoproteins, hemoglobin and myoglobin, once released from cells can cause severe oxidative damage as a consequence of heme redox cycling between ferric and ferryl states that generates radical species that induce lipid peroxidation. We demonstrate in vitro that acetaminophen inhibits hemoprotein-induced lipid peroxidation by reducing ferryl heme to its ferric state and quenching globin radical...

ژورنال: پژوهش در پزشکی 2011
دادخواه, ابوالفضل, داوودیان, ناهید, فاطمی, فائزه,

Abstract Background: Sepsis is a systemic response to severe infections leading to organ failure and death. Recently the role of herbal drugs in the management of the inflammatory response has come under increased scrutiny. Caraway is a well known traditional herbal plant believed to contain active components with pharmacological properties such as antioxidative effects. In this study attemp...

Elham Ghanbari , Mehri Azadbakht, Vahid Nejati ,

Background: Royal jelly has been shown to have antioxidant and antidiabetic effects. The objective of this study was to evaluate the protective effect of RJ against kidney damage in streptozotocin induced diabetic rats. Methods: Thirty two male Wistar rats were divided randomly into four groups (n=8 per group). Normal control and diabetic control groups received 1cc/day distilled water, norm...

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