نتایج جستجو برای: ki 67

تعداد نتایج: 83878  

2017
Xiaoming Qiu Jixin Mei Jianjun Yin Hong Wang Jinqi Wang Ming Xie

This study investigated expression of proliferating cell nuclear antigen (PCNA), proliferation-associated nuclear antigen (Ki-67) and cyclooxygenase-2 (COX-2) in tissues of breast invasive ductal carcinoma, and analyzed the correlations between these indexes and X-ray features in mammography. A total of 90 patients who were admitted to Huangshi Central Hospital and diagnosed as breast invasive ...

Journal: :Lung cancer international 2015
M G Joseph A Shibani N Panjwani A Arab J Shepherd L W Stitt R Inculet

Background. Evaluation of Ki-67 index in lung carcinoid tumors (LCTs) has been of interest in order to identify high risk subsets. Our objectives are (1) to evaluate the usefulness of Ki-67 index, mitoses, and tumor size in predicting metastasis and (2) to compare the Manual Conventional Method (MCM) and the Computer Assisted Image Analysis Method (CIAM) for Ki-67 calculation. Methods. We studi...

2015
Ping Wang Yu He Xiaodong Ma Beiwang Sun Binyuan Huang Canhua Zhu Yanmin Liu

BACKGROUND As an induced enzyme, COX-2 expression is elevated under stimuli from inflammatory mediator or growth factor product. Ki-67, a cell cycle-related proliferative antigen, reflects the tissue proliferative activity. This study analyzed the expressional profile of cyclooxygenase-2 (COX-2) and Ki-67 in hepatolithiasis and bile duct carcinoma tissues, in an attempt to provide evidence for ...

Journal: :Journal of cell science 1989
R Verheijen H J Kuijpers R van Driel J L Beck J H van Dierendonck G J Brakenhoff F C Ramaekers

In interphase cells the proliferation-associated antigen recognized by monoclonal antibody Ki-67 is almost exclusively located in the nucleoli. When cells at several stages of mitosis were examined for the localization of the Ki-67 antigen, a striking redistribution could be observed. During prophase the distinct nucleolar Ki-67 fluorescence changed to a bright irregular meshwork throughout the...

Journal: :Blood 2008
Olaf Determann Eva Hoster German Ott Heinz Wolfram Bernd Christoph Loddenkemper Martin Leo Hansmann Thomas E F Barth Michael Unterhalt Wolfgang Hiddemann Martin Dreyling Wolfram Klapper

Clinical outcome of mantle cell lymphoma (MCL) is highly heterogeneous. Tumor cell proliferation as assessed by the Ki-67 index has been shown to yield prognostic information on MCL in many studies using heterogeneously treated patient cohorts. The prognostic value of the Ki-67 index in patients treated with anti-CD20 therapy has not been studied so far. We analyzed the Ki-67 index at primary d...

2018
Syah Mirsya Warli Dhirajaya Dharma Kadar Ginanda Putra Siregar

BACKGROUND Bladder cancer is the 9th most frequent cancer worldwide. Ki-67 is immunohistochemistry marker that is predictive of cancer cell proliferation. The expression of Ki-67 is associated with poor prognosis in several types of malignancy, yet the value of Ki-67 as the prognostic factor in bladder cancer remains controversial. AIM This study is aimed to investigate the association betwee...

2017
Guanying Luo Yunzhao Hu Zhiqiao Zhang Peng Wang Zhaowen Luo Jinxin Lin Canchang Cheng You Yang

BACKGROUND The prognostic value and clinicopathologic significance of Ki-67 expression in gastric cancer patients was controversial. This meta-analysis was performed to clarify the prognostic value and clinicopathologic significance of Ki-67 expression in gastric cancer patients. MATERIALS AND METHODS Several electronic databases were searched for eligible studies. The pooled odds ratio (OR),...

2017
Yunbao Pan Yufen Yuan Guoshi Liu Yongchang Wei

Triple-negative breast cancer (TNBC) is an aggressive subgroup of breast cancer lack of effective target therapy. This study was to investigate the prognostic role of p53 and Ki-67 in 156 cases of TNBC patients. Logistic regression analysis was used to examine the association between clinical parameters and recurrence. Univariate and multivariate analyses were used to examine the association be...

Journal: :Folia biologica 2014
Adam Brodzki Wojciech Łopuszyński Piotr Brodzki Marcin R Tatara

In the perianal region of carnivores, skin consists of modified sebaceous glands called perianal glands. Tumors originating from perianal glands are the third most frequent type of neoplasm in male dogs after neoplastic diseases of testes and skin. Ki-67 is a nuclear non-histone protein considered a proliferation marker in normal and neoplastic proliferating cells. Previous investigations revea...

2017
Richard Menger David E Connor Jr. Alvin Y Chan Gary Jain Anil Nanda

Objective Meningioma recurrence after resection is likely influenced by multiple surgical and histologic factors. In this study, the degree of resection and tumor immunoreactivity to MIB-1 (i.e., Ki-67 labeling index (LI)) are described in recurrent and non-recurrent meningioma cases. Methods Data regarding tumor location, the degree of resection, histologic features, and the degree of Ki-67 po...

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