Attachment invasion locus (Ail) protein of Yersinia pestis is a crucial outer membrane protein for host invasion and determines bacterial survival within the host. Despite its importance in pathogenicity, surprisingly little is known on Ail biophysical properties. We investigate the contribution of micelle concentrations and interface tryptophans on the Ail β-barrel refolding and unfolding proc...

We have carried out molecular dynamics simulations of the naturally occurring protegrin PG-1 peptide and two of its mutants, PC-9 and PC-13 in the presence of a dodecyl-phosphocholine (DPC) micelle. The effects of mutations that disrupt the β-sheet structure in the case of PC-9 and reduce the charge at the C-terminus in the case of PC-13 are analyzed. It is found that the surface-bound conforma...

The purpose of this study was to evaluate the potential of micelle to change the pharmacokinetics of quercetin (QUT), with a primary goal of enhancing its oral bioavailability. QUT-loaded methoxy poly(ethylene glycol)-b-poly(L-lactic acid) micelle (QUT-loaded MPEG-b-PLLA micelle) was prepared by a thin-film hydration method, resulting in a particle size of 88.5 nm. A liquid chromatography tande...

filament stretching extensional rheometer and capillary breakup extensional rheometer are used o measure the extensional rheology of a series of wormlike micelle solutions experiencing a niaxial elongational flow. The experiments are performed using a series of wormlike micelle olutions of both cetylpyridinium chloride and sodium salicylate NaSal in an aqueous sodium hloride solution and cetylt...

This document gives formatting guidelines for authors preparing papers for publication in the International Journal of Emerging Technology and Advanced Engineering The authors must follow the instructions given in the document for the papers to be published. Keywords—Keyword are your own designated keyword which can be used for easy location of the manuscript using any search engines. It includ...

Keyword-based linked data information retrieval is an easy choice for general-purpose users, but the implementation of such an approach is a challenge because mere keywords do not hold semantic information. Some studies have incorporated templates in an effort to bridge this gap, but most such approaches have proven ineffective because of inefficient template management. Because linked data can...

The elongated shape of linear, worm-like, micelles is among the most common aggregation geometries of amphiphilic molecules in aqueous solutions. The cylindrical body of these uni-dimensional micelles can be regarded as an intermediate packing geometry, of a higher growth dimensionality than that of a spherical micelle and lower than that of a planar bilayer. In all these three canonical struct...

Introduction . Keywords, reflecting the main content of article, play an extremely important role in search for scientific papers databases. Together with title and abstract, keywords provide primary information about study. Selecting extracting effective is a time-consuming process, so its optimization requires further studying. Purpose. The article aimed at acquainting authors journal methods...