نتایج جستجو برای: keywords measurement systems analysis msa

تعداد نتایج: 5491059  

Journal: :Archives of neurology 2011
Claudia Moreno-López Joan Santamaría Manuel Salamero Francesca Del Sorbo Alberto Albanese Maria Teresa Pellecchia Paolo Barone Sebastiaan Overeem Bastiaan Bloem Willemijn Aarden Margherita Canesi Angelo Antonini Susanne Duerr Gregor K Wenning Werner Poewe Alfonso Rubino Giuseppe Meco Susanne A Schneider Kailash P Bhatia Ruth Djaldetti Miguel Coelho Cristina Sampaio Valerie Cochen Helge Hellriegel Günther Deuschl Carlo Colosimo Luca Marsili Thomas Gasser Eduardo Tolosa

BACKGROUND Sleep disorders are common in multiple system atrophy (MSA), but the prevalence of excessive daytime sleepiness (EDS) is not well known. OBJECTIVE To assess the frequency and associations of EDS in MSA. DESIGN Survey of EDS in consecutive patients with MSA and comparison with patients with Parkinson disease (PD) and individuals without known neurologic disease. SETTING Twelve t...

2008
Charles R. McLean Sanjay Jain Y. Tina Lee

The effective use of modeling, simulation, and analysis (MSA) applications could greatly enhance our nation’s ability to achieve homeland security goals. The development of MSA applications has been conducted largely on an ad hoc and piecemeal basis. There is very little, if any, coordination of MSA development activities across government agencies, the research community, the commercial softwa...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Rolf von Knobloch Heidrun Brandt Andres J Schrader Axel Heidenreich Rainer Hofmann

PURPOSE To evaluate the efficacy of fluorescent microsatellite analysis (MSA) for the serological diagnosis of transitional cell carcinoma (TCC) of the urinary tract analyzing free tumor DNA in the serum of cancer patients. EXPERIMENTAL DESIGN We applied fluorescent MSA to detect serum-DNA alterations in patients suffering from bladder and upper urinary tract TCC and prospectively collected f...

2017
Thomas Lanyon-Hogg Neki V. Patel Markus Ritzefeld Katherine J. Boxall Rosemary Burke Julian Blagg Anthony I. Magee Edward W. Tate

The Hedgehog pathway is a key developmental signaling pathway but is also implicated in many types of cancer. The extracellular signaling protein Sonic hedgehog (Shh) requires dual lipidation for functional signaling, whereby N-terminal palmitoylation is performed by the enzyme Hedgehog acyltransferase (Hhat). Hhat is an attractive target for small-molecule inhibition to arrest Hedgehog signali...

2002
Dannie Durand Martin Farach-Colton

Multiple sequence alignment (MSA) is important in functional, structural and evolutionary studies of sequence data. While MSA construction has traditionally been an interactive process, the rapid growth of genetic sequence data has engendered a need for automated sequence analysis without human intervention. This requires more accurate methods based on rigorous mathematical models that reflect ...

2013
Ruchi Gupta A. K. Soni Pankaj Agarwal

1 Assistant Professor, AKGEC Ghaziabad, India, Ph.D Research Scholar 2 Professor & Head, Department of Computer Science & Engineering, Sharda University, Greater Noida, India 3 Professor & Head, Department of Computer Science & Engineering, IMS Engineering College Ghaziabad, India _____________________________________________________________________________________ Abstract: Multiple Sequence A...

2012
Heba Elfardy Mona T. Diab

The Arabic language is a collection of dialectal variants along with the standard form, Modern Standard Arabic (MSA). MSA is used in official Settings while the dialectal variants (DA) correspond to the native tongue of the Arabic speakers. Arabic speakers typically code switch between DA and MSA, which is reflected extensively in written online social media. Automatic processing such Arabic ge...

Journal: :Archives of neurology 2007
Kenju Hara Yoshio Momose Susumu Tokiguchi Mitsuteru Shimohata Kenshi Terajima Osamu Onodera Akiyoshi Kakita Mitsunori Yamada Hitoshi Takahashi Motoyuki Hirasawa Yoshikuni Mizuno Katsuhisa Ogata Jun Goto Ichiro Kanazawa Masatoyo Nishizawa Shoji Tsuji

BACKGROUND Multiple system atrophy (MSA) has been considered a sporadic disease, without patterns of inheritance. OBJECTIVE To describe the clinical features of 4 multiplex families with MSA, including clinical genetic aspects. DESIGN Clinical and genetic study. SETTING Four departments of neurology in Japan. Patients Eight patients in 4 families with parkinsonism, cerebellar ataxia, and ...

2006
Yue Li Lan Luo Tao Li Tamer Kahveci

With the growth of bioinformatics and computational biology industry, multiple sequence alignment (MSA) applications have become an important emerging workload. In spite of the large amount of recent attention given to the MSA software design, there has been little quantitative understanding of the performance of such applications on modern microprocessors and systems. In this paper, we analyze...

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