Harmine, a β-carboline alkaloid, is a high affinity inhibitor of the dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) protein. The DYRK1A gene is located within the Down Syndrome Critical Region (DSCR) on chromosome 21. We and others have implicated DYRK1A in the phosphorylation of tau protein on multiple sites associated with tau pathology in Down Syndrome and in Alzheime...

This document gives formatting guidelines for authors preparing papers for publication in the International Journal of Emerging Technology and Advanced Engineering The authors must follow the instructions given in the document for the papers to be published. Keywords—Keyword are your own designated keyword which can be used for easy location of the manuscript using any search engines. It includ...

Keyword-based linked data information retrieval is an easy choice for general-purpose users, but the implementation of such an approach is a challenge because mere keywords do not hold semantic information. Some studies have incorporated templates in an effort to bridge this gap, but most such approaches have proven ineffective because of inefficient template management. Because linked data can...

Introduction . Keywords, reflecting the main content of article, play an extremely important role in search for scientific papers databases. Together with title and abstract, keywords provide primary information about study. Selecting extracting effective is a time-consuming process, so its optimization requires further studying. Purpose. The article aimed at acquainting authors journal methods...

Acta Academica is an accredited, open access South African journal dedicated to scholarship in the humanities. The publishes independently refereed research articles It promotes perspectives of critical social theory and engagements with postcolonial post-developmental debates special references (Southern) Africa. thereby support scholarly work that examines how humanities twenty-first century ...