نتایج جستجو برای: kennedy disease

تعداد نتایج: 1493363  

2014
P. J. SCHROEDER Robert Kennedy

S en a to r R o b ert F . K ennedy has em erged the v ic to r in his first P rim ary clash w ith S enato r Eugene M cC arthy fo r th e D em o­ cratic P residen tial nom ina tion . The Ind iana P rim ary, m uch to u te d as th e definitive con­ tes t be tw een K ennedy and Me C arthy , has resu lted in an over­ w helm ing v icto ry fo r S enator K ennedy . A m uch heavier tu rn o u t o f vo ters...

2009
S. E. Joel P. Srinivasan S. Spinelli S. H. Mostofsky J. J. Pekar

S. E. Joel, P. Srinivasan, S. Spinelli, S. H. Mostofsky, and J. J. Pekar Radiology, Johns Hopkins University, Baltimore, MD, United States, FM Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States, Laboratory for Neurocognitive and Imaging Research, Kennedy Krieger Institute, Baltimore, MD, United States, Neurology, Johns Hopkins University,...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Felicity Payne Koini Lim Amandine Girousse Rebecca J Brown Nora Kory Ann Robbins Yali Xue Alison Sleigh Elaine Cochran Claire Adams Arundhati Dev Borman David Russel-Jones Phillip Gorden Robert K Semple Vladimir Saudek Stephen O'Rahilly Tobias C Walther Inês Barroso David B Savage

Phosphatidylcholine (PC) is the major glycerophospholipid in eukaryotic cells and is an essential component in all cellular membranes. The biochemistry of de novo PC synthesis by the Kennedy pathway is well established, but less is known about the physiological functions of PC. We identified two unrelated patients with defects in the Kennedy pathway due to biallellic loss-of-function mutations ...

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