This case report describes a 41-year-old Afro-Caribbean lady presenting with a constellation of pyrexia, conjunctivitis, arthralgia, sterile dysuria, apthous ulceration, labial crusting and widespread erythema multiforme. A diagnosis of Stevens-Johnson Syndrome was made. She had taken no medications recently (the most common precipitant of Stevens-Johnson Syndrome) and a full screen for the com...

Fuchs' syndrome (Stevens-Johnson syndrome without skin involvement) is a sporadically diagnosed disease. Most authors consider it to be a pure mucosal variant of Stevens-Johnson syndrome; however, some consider the syndrome a separate entity. The complete absence of cutaneous symptoms may be the reason that not all cases of Fuchs' syndrome are diagnosed and properly classified. The authors desc...

PURPOSE To evaluate the epidemiology, possible etiologic factors, complications and treatment of a group of patients with ocular complications secondary to Stevens-Johnson syndrome. METHODS Twenty-two consecutive patients with Stevens-Johnson syndrome were studied. The patients were examined according to the following protocol: identification, previous clinical history, systemic and ophthalmo...

OBJECTIVE Toxic epidermal necrolysis and Stevens-Johnson syndrome have related high morbidity and mortality. We predict that preexisting multimorbidity is a major prognostic factor of both these diseases. METHODS A retrospective analysis in toxic epidermal necrolysis and Stevens-Johnson syndrome patients over the past 10 years. Three severity categories (minor, moderate, and severe multimorbi...

Cholestasis may be defined as stagnation of bile within the intrahepatic or extrahepatic biliary tree. Biochemically, there is retention of conjugated bilirubin, bile salts, and alkaline phosphatase; morphologically, there is at least dilatation of biliary canaliculi and loss of their microvilli, and later accumulation of bile pigment in the canaliculi (bile plugs)."0 The mechanism underlying t...

Due to fever, lymphadenopathy and rash, this condition has to be differentiated from viral infections especially infectious mononucleosis and also bacterial infections. Awareness of this entity helps in an early diagnosis. Treatment consists of omitting the offending drug and systemic steroids, if necessary. Our patient was managed symptomatically. REFERENCES 1. Mittal RR, Jain C, Walia RLS, Ch...

The Stevens-Johnson syndrome has the appearance of a partial-thickness burn that may lead to a 100% loss of epidermis, requiring the same resuscitation as a severe burn. A 38-yr-old male patient was admitted to the neurosurgery department of the Evangelismos General Hospital in Athens, where immediately after administration of an antiepileptic drug he developed sloughing of total epidermis, hig...

The Stevens-Johnson Syndrome, otherwise known as erythema multiforme exudativum, has lately become more widely recognised as being liable to present as an acute medical emergency. The case described here is of special interest for several reasons: it would seem to be the most severe example of the disease ever recorded, which did not end fatally; it was complicated by acute dysphagia necessitat...

There are many disorders associated with direct hyperbilirubinemia in the neonatal period. These usually need urgent referral to identify treatable diseases. DubinJohnson Syndrome (DJS), which results from impaired hepatic excretory function, is an uncommon cause of neonatal jaundice and is only sporadically reported in neonates. We report here a neonate who presented with direct hyperbilirubin...