background: the aim of the present study was to investigate the immunomodulation effects of aqueous garlic extract (age) in the cultured macrophages infected by leishmania major . methods: after j774 macrophages proliferation in rpmi1640 and incubation with leishmania for 72 hours, age was added in doses of 9.25, 18.5, 37, 74 and 148 mg/ml for 18, 24 and 48 hours and cell culture supernatants w...

Gliocladium sp. FO-1513 was found to produce novel inhibitors of acyl-CoA: cholesterol acyltransferase (ACAT). Twoactive compounds, designated glisoprenins A and B, were isolated from the culture broth of the producing strain by a conventional method. The IC50 values of glisoprenins A and B for ACATactivity were 46 and 61fiM in an enzyme assay using rat liver microsomes, and 1.2 and 0.57 /^M in...

The intracellular survival of Campylobacter has been described within epithelial cells as well as in macrophages in vitro. The goal of this study was to estimate the viability of the genetically diverse C. jejuni and C. coli strains in the macrophage J774 cell line. Strains selected for analysis differed with regard to the occurrence of genes encoding specific virulence factors. The present wor...