Recently, we reported five Japanese patients with large B-cell lymphoma associated with hemophagocytic syndrome, ie, malignant histiocytosis-like B-cell lymphoma, and suggested that they might be regarded as an aggressive variant of intravascular lymphomatosis (IVL) based on the localization of tumor cells within the sinus and vessels of the involved organs.1 Phenotypically, these lymphomas wer...

The Changing Landscape of Cardiogenic Shock: One Step Closer to Speaking a Common TongueJournal the Society for Cardiovascular Angiography & InterventionsVol. 1Issue 1100012Preview“Progress is impossible without change, and those who cannot change their minds anything.” George Bernard Shaw (1944) Full-Text PDF Open AccessOutcomes Novel Supreme Drug-Eluting Stent in Complex Coronary Lesions: A P...

•Although the dynamic expansion mechanism allows transient enlargement of Edwards Commander Delivery System, in severely calcified and stenotic iliofemoral arteries, eSheath may not be able to expand adequately during transcatheter heart valve advancement allow a smooth passage.•Excessive push force necessary engage advance but risk damaging as shown our initial case. Worse yet, get stuck, majo...

A large part of the coding region of the hominoid involucrin gene is of recent origin. This part of the gene, which we have called the modern segment, contains numerous repeats of a sequence of 10 codons, created by multiple duplications some of which consist of 3-12 repeats. We have sequenced two alleles of the involucrin gene in the owl monkey and found that the involucrin gene of this specie...

PURPOSE To explore the roles of STAT3 in the regulation of ΔNp63-dependent proliferation and differentiation of rabbit limbal keratinocytes. METHODS siRNAs were designed to specifically suppress the expression of STAT3 and ΔNp63, and their effects on limbal epithelial cell proliferation and differentiation were examined. Ectopically expressed ΔNp63 was used to compensate for the decreased end...

TOPIC: Critical Care TYPE: Fellow Case Reports INTRODUCTION: Intravascular lymphoma (IVL) is a rare subtype of proliferating in the lumen causing small vessel occlusion. Antemortem diagnosis difficult. The majority cases are diagnosed from autopsy. We report patient with IVL who presented sepsis unknown source complicated by multiorgan failure. CASE PRESENTATION: A 58-year-old male hypertension...

Inherited ichthyoses represent a large heterogeneous group of skin disorders characterised by impaired epidermal barrier function and disturbed cornification. Current knowledge about disease mechanisms has been uncovered mainly through the use mouse models or human organotypic models. However, most lines suffer from severe defects causing neonatal death keratinocytes have very limited prolifera...

The vertical alignment design method of road in scenic spots does not evolve enough along the vehicle’s rapid variation. Values maximum longitudinal slope (MLS) and longest length (LSL) applicable to roads used by environmental-friendly vehicle (EFV) are provided. To compensate for this shortage, a multibody dynamic model uphill traving is built, providing static equilibrium state balancing pro...