PURPOSE Seasonal and perennial allergic conjunctivitis represent the majority of cases of ocular allergy. This analysis was designed to evaluate the efficacy and safety of once-daily alcaftadine 0.25% in preventing ocular itching associated with seasonal or perennial allergic conjunctivitis. SUBJECTS AND METHODS Pooled data from two double-masked, multicenter, placebo-controlled studies using...

Burn therapies should focus on achieving outcomes that are most important to patients. The authors wanted to discover which outcomes newly burned patients would anticipate as most important to them and explored the association between demographic/burn characteristics and patient preferences. The authors surveyed 753 of 776 patients seen by our burn service from 2008 to 2013 during the initial e...

Vulvo-vaginal symptoms are among the most common reasons that women seek health care; upward of 6 million physician office visits are made by women of all age ranges for vulvo-vaginal symptoms. Despite such staggering statistics, most clinicians are not adequately prepared to diagnose and treat chronic vulvo-vaginal symptoms. Overlapping clinical appearance, symptoms, and pathophysiology, compo...

1Laboratory of Skin Neurobiology, University of Brest, 2Department of Dermatology, University Hospital of Brest, 3Public Health, Pierre Fabre, 4Ducray Laboratories, Lavaur, France. Context Pruritus, or itch, is an unpleasant feeling that leads to the need to scratch. A study of pruritus at the community level could offer significant information on its association with demographic and psychosoci...

In atopic dermatitis (AD), severe itching and scratching not only impacts the patient's quality of life, but also exacerbates the disease; however, the precise underlying mechanisms of itching in AD remain elusive. We have previously reported a special diet-induced, mouse model of AD. This article reviews the characteristics of the model, and the chronological and pharmacological analyses of th...