Dog Rose is one of the most important species in Rosaceae family used as a medicinal plant and a rootstock for ornamental roses. This species is native to Iran, therefore, identification of indigenous genotypes of this species is important for genetic preservation or breeding purposes. Genetic diversity estimation of plant materials is one of the important pre-breeding activities in breeding cr...

To determine whether thymidine kinase (TK) isozyme status adds clinically useful information in adult nonHodgkin’s lymphoma (NHL). we have analyzed peripheral blood plasma and lymphocytes of 44 patients with NHL for either TK1 or TK2 isozyme activity. On the basis of isozyme status. patients could be divided into two groups that did not differ significantly with respect to known determinants fo...

Molecular layer inhibitory interneurons generate on-beam and off-beam inhibition in the cerebellar cortex that is hypothesized to control the timing and/or spatial patterning of Purkinje cell discharge. On- and off-beam inhibition has been assumed to be spatially uniform and continuous within a folium. Using flavoprotein autofluorescence optical imaging in the mouse cerebellar cortex in vivo, t...

Thirteen electrophoretic bands of lactate dehydrogenase isoenzyme activity were detected in the serum of a 69-year-oldNegro woman who died of pseudomonas pneumonia. No evidence of tumor was found at necropsy, and additional studies of the enzymatic activity of crude extracts of liver, lung, spleen, kidney, brain, skeletal muscle, lymph node, and heart revealed 1, 2, 3, 4, and 5 separate lsoenzy...

Two isozymes of glutamate dehydrogenase were shown to exist in a thermophilic strain of Chlorella pyrenoidosa. The NADPH:NADH activity ratios of the NADHand NADPHspecific isozymes were 1: 5 and 33: 1, and the molecular weights were estimated to be 179,000 and 269,000, respectively. Only the NADH-specific isozyme was detectable in nitrate-cultured cells; the synthesis of the NADPH-specific isozy...

Isozyme 4 of rabbit liver microsomal cytochrome P-450 was shown earlier in this laboratory to contain multiple NH2-terminal residues, whereas isozymes 2, 3a, 3b, and 3c have single, unique NH2-terminal sequences. Similar results were obtained with isozyme 4 obtained from animals that were untreated, treated with phenobarbital (which does not induce this isozyme), or induced with beta-naphthofla...

In a recent study on Gulf War veterans who developed delayed neurotoxicity symptoms, we found their levels of serum paraoxonase (PON1) isozyme type Q to be significantly lower than in the control, unaffected veteran group. These results were obtained 25 ill and 20 well control subjects, which 10 deployed nondeployed battalion members remained United States during War. The blood samples also ass...