OBJECTIVES We sought to determine if the nitric oxide (NO) donor isosorbide mononitrate (ISMN) (200 mg/kg body weight/day) decreases vascular bioavailability of superoxide in atherosclerosis. BACKGROUND Vascular oxidative stress limits the bioavailability of endothelial NO and promotes atherosclerosis, while NO itself exerts antioxidative effects. It is unknown if therapeutic NO impacts on va...

Pulmonary hypertension is uncommonly associated with portal hypertension. The current approach for the management of pulmonary hypertension involves the use of vasodilators in patients who show vascular responsiveness during an acute challenge. Since the association of portal hypertension with pulmonary hypertension is very seldomly presented, its optimal therapy has not been defined. Moreover,...

In situ soil moisture measurements are invaluable for calibrating and validating land surface models and satellite-based soil moisture retrievals. On a worldwide basis the number of meteorological networks measuring soil moisture is still limited and their data lack standardization of technique and protocol. In response to this, the International Soil Moisture Network (ISMN) was initiated to se...

diode doped by organic molecules D. Krautz, E. Lunedei, J. Puigdollers, G. Badenes, R. Alcubilla, and S. Cheylan ICFO-Institut de Ciencies Fotoniques, Mediterranean Technology Park, 08860 Castelldefels (Barcelona), Spain ISMN-CNR, Institute for the Study of Nanostructured Materials, 40129 Bologna, Italy Departamento de Ingeniería Electrónica, Universidad Politécnica de Cataluña–UPC, 08034 Barce...

Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator effects improving symptoms in patients with acute and chronic congestive heart failure, stable coronary artery disease, acute coronary syndromes, or arterial hypertension. The mechanisms underlying vasodilation inc...