Carob leaves (Ceratonia siliqua L.), grown in Egypt have not fully identified in Egypt. Therefore, eight major phenolic compounds were isolated from the aqueous ethanolic extract using different methods of chromatography; gallic acid, quercetin 3-O-4C1-B-D-glucoside (Isoquercetin), Kaempferol 3-O1C4-"-Lrhamnoside (Afzelin), Quercetin 3-O-1C4-"-L-rhamnoside (Quercitrin), 1,2,6 tri-O-galloyl-B-D4...

alpha-Glycosyl isoquercitrin (AGIQ) is highly absorbable and has been shown to possess antioxidative properties. Based on a favorable safety profile, it has been confirmed as generally recognized as safe (GRAS) compound by the FDA. Nevertheless, safety and toxicity information for AGIQ is still sparse. Therefore, the aim of this study was to test the safety and toxicokinetics of AGIQ in a 90-da...

BACKGROUND Enzymatically modified isoquercitrin (EMIQ) is produced from rutin using enzymatic hydrolysis followed by treatment with glycosyltransferase in the presence of dextrin to add glucose residues. EMIQ is absorbed in the same way as quercetin, a powerful antioxidant reported to prevent disused muscle atrophy by targeting mitochondria and to have ergogenic effects. The present study inves...

In this study, type II collagen was used to induce arthritis in mice test the effect and mechanism of dandelion tea. The visual manifestations arthritis, histopathological conditions spleen, serum inflammatory factors gene expression synovium foot ankle joints were detected by methods index (AI), spleen index, enzyme linked immunosorbent assay (ELISA), hematoxylin-eosin (H&E) staining quantitat...

Romanian traditional medicine describes the use of aerial parts of Fumaria species to treat hepatobiliary diseases as well as diuretic agents. The present study aims to investigate the chemical composition, antioxidant properties, and diuretic effects of several Fumaria species. LC/MS analysis revealed that Fumaria species contain phenolic acids and high amounts of flavonoids with rutin and iso...

Nine flavonoid compounds: kaempferol 3-0-beta-(6"-p-coumaroyl)-glucopyranoside, myricetin 3-O-beta-glucopyranoside, quercetin 3-0-beta-glucopyranoside, quercetin 3-0-alpha-rhamnopyranosyl (1-->6)-beta-glucopyranoside, kaempferol 3-0-beta-glucopyranoside, kaempferol 3-0-alpha-rhamnopyranosyl (1-->6)-beta-glucopyranoside, quercetin 7-0-beta-glucoside, quercetin 7-0-beta-diglucoside, kaempferol 7-...

A pectolytic enzyme preparation from Aspergillus niger (pectinase AN) decreased most rutin content and antioxidant activity of asparagus juice. To investigate the mechanism of such loss, we analyzed several possible related enzyme activities in pectinase AN. We found that the activity of pectinase AN to oxidize guaiacol had no significant difference with or without the presence of H2O2; thus it...