objective(s) the aim of this study was to investigate the overall effect of cardiac vasoactive factors during coronary occlusion and reperfusion on peripheral vascular tone, using a sequential isolated rabbit heart-ear perfusion model. materials and methods isolated ears were perfused with the effluent of isolated hearts subjected to ischemia (30 min) and reperfusion (180 min, n=6). the compara...

purpose: to report a case of posterior ischemic optic neuropathy (pion) following percutaneous nephrolithotomy (pcnl). patient and findings: a 57-year-old male who underwent pcnl because of renal stone was referred due to painless bilateral visual loss to the level of light perception immediately after the operation. the patient had history of diabetes mellitus, hyperlipidemia, and mild anemia....

purpose : to evaluate the correlations between visual field (vf) defects with retinal nerve fiber layer (rnfl) thickness in nonarteritic anterior ischemic optic neuropathy (naion) eyes, compare different gdx parameters with the other healthy contralateral eyes, and calculate receiver operating characteristic (roc) curve for the gdx parameters methods : eighteen patients with unilateral naion fr...

background: ischemic heart disease (ihd) is one of the leading causes of death and disability among young and older women, respectively. researches in this area mostly focused on manifestations, risk factors, and treatment of the patients with ihd. therefore, there is a lack of information on the aspects of affects and feelings of such patients. this study aimed to describe lived experience of ...

background: more than half of myocardial infracted (mi) patients have no conventional risk factors. regarding the belief that opium addiction has a protective effect on heart diseases, addiction prevalence has unfortunately increased in recent years. this study was conducted to investigate the effect of opium addiction on patients with acute myocardial infarction. methods: this case-control stu...

preconditioning (pc), is an approach to improve therapeutic potential of stem cells against ischemic environment. pc has several advantages over other therapeutic techniques as this results in increase of transplanted stem cells recruitment, retention, survival and subsequently the induction of a more supportive environment within the damaged tissue via secretion of angiogenic factors. special ...

Introduction: Using brief episodes of ischemia and reperfusion (IR) prior to a more sustained IR insult – ischemic preconditioning (IPC) – can reduce IR injury of the heart, brain and many other tissues. The purpose of present study was to investigate the effect of 2min ischemic periods on subsequent rat renal IR injury. Methods: Male rat's renal IR injury was investigated in a right nephrectom...

background & aim: stroke in young adults is rare but can be devastating for the affected individuals and their families. some triggers of stroke may be acute but transient effects on the pathophysiological condition while other factors may be effective overa longer period. methods & materials: this study was a case-crossover study on 18 young adults. the study included patients aged 15-49 years...

the anti-ischemic effect of aqueous and ethanolic extracts of nigella sativa l. seed was studied using a four-vessel occlusion model in rats. the ischemia was evaluated by optical and transmission electron microscopy. after 20 min of forebrain ischemia, agents were administered intraperitoneally after reperfusion. both extracts comprised an alkaloid. in ischemic rats, the aqueous (1 g/kg) and e...